Laura Saba

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Associate Professor

University of Colorado Denver School of Pharmacy

United States

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About

Laura Saba is an Associate Professor at the University of Colorado Denver School of Pharmacy. Her research primarily focuses on immunocompatibility, transcriptomic analysis, and the effects of various compounds on the neurobiology and pharmacogenetics of different species. Recent publications include studies on the impacts of dexamethasone on ocular health, as well as investigations into the complexities of immune responses related to nanomedicines and cannabis use. She is dedicated to advancing the understanding of genetic and biochemical pathways relevant to health and disease.

Recent Grants

Grant: Close

Identification of genes and genetic networks contributing to opioid use disorder traits in the Hybrid Rat Diversity Panel

Open Date: 2020-08-01

Close Date: 2025-05-31

Grant: Close

Overall NIDA Core "Center of Excellence" in Transcriptomics, Systems Genetics and the Addictome

Open Date: 2017-08-01

Close Date: 2023-05-31

Grant: Close

The Heritable Transcriptome and Alcoholism

Open Date: 2001-08-01

Close Date: 2023-07-31

Articles (13)

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2025

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2024

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2022

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2022

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2021

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2021

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2021

Collaborators (11)

Jay Hesselberth

Associate Professor

University of Colorado School of Medicine

UNITED STATES

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Rajesh Agarwal

UNITED STATES

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Spencer Mahaffey

Principal IT Professional

University of Colorado Anschutz Medical Campus

UNITED STATES

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Marissa A. Ehringer

UNITED STATES

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Brent Kisby

Texas Tech University Health Sciences Center

UNITED STATES

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Nirmal K. Banda

University of Colorado Boulder

UNITED STATES

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Komal Raina

UNITED STATES

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Seyed Moein Moghimi

Professor of Pharmaceutics and Nanomedicine

Newcastle University

UNITED KINGDOM

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Sushil Kumar

University of Denver

UNITED STATES

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Layne Dylla

Assistant Professor

Yale University

UNITED STATES

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Hao Chen

Professor

University of Tennessee Health Science Center

UNITED STATES

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Laura Saba

Research Interests

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About

Recent Grants

Articles (13)

Dexamethasone alters the cornea transcriptome to confer protection against ocular sulfur mustard exposure via regulating NFκB and TGFβ signaling in an in vivo rabbit model

Enhanced Immunocompatibility and Hemocompatibility of Nanomedicines Across Multiple Species Using Complement Pathway Inhibitors

Nanoparticle-Binding Immunoglobulins Predict Variable Complement Responses in Healthy and Diseased Cohorts

The regulatory landscape of multiple brain regions in outbred heterogeneous stock rats

Hippocampal RNA sequencing in mice selectively bred for high and low activity

Evaluation and characterization of expression quantitative trait analysis methods in the Hybrid Rat Diversity Panel

Antibody-Dependent Complement Responses toward SARS-CoV-2 Receptor-Binding Domain Immobilized on “Pseudovirus-like” Nanoparticles

Beyond Genes: Inclusion of Alternative Splicing and Alternative Polyadenylation to Assess the Genetic Architecture of Predisposition to Voluntary Alcohol Consumption in Brain of the HXB/BXH Recombinant Inbred Rat Panel

An Approach to Biomarker Discovery of Cannabis Use Utilizing Proteomic, Metabolomic, and Lipidomic Analyses

Sex Differences in the Brain Transcriptome Related to Alcohol Effects and Alcohol Use Disorder

Transcriptome and metabolome changes induced by bitter melon (<i>Momordica charantia</i>)- intake in a high-fat diet induced obesity model.

Complement opsonization of nanoparticles: Differences between humans and preclinical species

Correction to “Complement Inhibitors Block Complement C3 Opsonization and Improve Targeting Selectivity of Nanoparticles in Blood”

Collaborators (11)

Jay Hesselberth

Rajesh Agarwal

Spencer Mahaffey

Marissa A. Ehringer

Brent Kisby

Nirmal K. Banda

Komal Raina

Seyed Moein Moghimi

Sushil Kumar

Layne Dylla

Hao Chen

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