Layne Dylla

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Assistant Professor

Yale University

United States

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About

Layne Dylla is an Assistant Professor at Yale University in the United States. His research primarily focuses on stroke care, kynurenine metabolism, and immunological responses, as evidenced by his recent articles exploring post-stroke infection, prehospital stroke care, and metabolic differences during acute ischemic events. Additionally, he investigates nanoparticle interactions and their implications in both healthy and diseased populations.

Recent Grants

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The Role of Hyperoxia in the Emergency Department Treatment of Acute Ischemic Stroke

Open Date: 2019-04-01

Close Date: 2022-03-31

Grant: Close

The Sex-Based Differences in Response to Hyperoxia for Acute Ischemic Stroke

Open Date:

Close Date:

Grant: Close

Sex-based Differences in the Metabolic Response to Stroke

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Close Date:

Grant: Close

Sex-based Differences in the Ischemic-Reperfusion Response to Hyperoxia for the Treatment of Acute Ischemic Stroke

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Articles (10)

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2025

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2024

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

Collaborators (1)

Laura Saba

Associate Professor

University of Colorado Denver School of Pharmacy

UNITED STATES

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Layne Dylla

Research Interests

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About

Recent Grants

Articles (10)

Elevated initial blood kynurenine is associated with increased odds of post-stroke infection: Kynurenine and post-stroke infection

Nanoparticle-Binding Immunoglobulins Predict Variable Complement Responses in Healthy and Diseased Cohorts

Identification of specific recommendations for prehospital stroke care associated with shorter door-to-CT times – An analysis of Get with the Guidelines-Stroke registry and prehospital data

Optimized Enzyme-Linked Immunosorbent Assay for Anti-PEG Antibody Detection in Healthy Donors and Patients Treated with PEGylated Liposomal Doxorubicin

Sex Differences in Tryptophan Metabolism via the Kynurenine Pathway in Acute Ischemic Stroke

Sex Differences in the Blood Metabolome During Acute Response to Ischemic Stroke

Validation of dot blot immunoassay for measurement of complement opsonization of nanoparticles

Sex differences in acute ischemic stroke presentation are a matter of infarct location.

A Multi-Omic Mosaic Model of Acetaminophen Induced Alanine Aminotransferase Elevation.

Hyperoxia is associated with a greater risk for mortality in critically ill traumatic brain injury patients than in critically ill trauma patients without brain injury.

Collaborators (1)

Laura Saba

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