Leemor Joshua-Tor

Professor and HHMI Investigator

United States

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About

Leemor Joshua-Tor is a Professor and HHMI Investigator at the Howard Hughes Medical Institute, Cold Spring Harbor Laboratory in the United States. His research focuses on molecular mechanisms in various contexts, including the phosphorylation of glycated substrates, RNA structure unraveling, and enhancer activation in Ewing sarcoma. Additionally, he investigates DNA replication origin specification and the dynamics of protein complexes through advanced imaging techniques.

Articles (9)

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2025

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2023

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2023

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2023

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2022

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2022

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2022

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Imperial College London

UNITED KINGDOM

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Leemor Joshua-Tor

Research Interests

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About

Articles (9)

The molecular basis of Human FN3K mediated phosphorylation of glycated substrates

ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation

Manipulating PTPRD function with ectodomain antibodies

A shape-shifting nuclease unravels structured RNA

OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage

Developmental roles and molecular mechanisms of Asterix/GTSF1

Target binding triggers hierarchical phosphorylation of human Argonaute-2 to promote target release

Evolution of DNA replication origin specification and gene silencing mechanisms

The dynamic nature of the human origin recognition complex revealed through five cryoEM structures

Collaborators (5)

Mikala Egeblad

Justin Kinney

Bruce Stillman

Xue-Yan He

Christian Speck

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