Xue-Yan He

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Assistant Professor

Washington University in St. Louis

United States

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About

Xue-Yan He is an Assistant Professor at Washington University in St. Louis, USA. His research focuses on the role of neutrophils in cancer progression and metastasis, and the interplay between host responses and tumor microenvironments. His recent publications explore topics ranging from tumor immunology to the effects of chronic stress on metastatic behavior.

Recent Grants

Grant: Close

Targeting stress-induced neutrophil extracellular traps prevents metastasis

Open Date: 2021-07-01

Close Date: 2023-06-30

Grant: Close

Targeting cancer cell CCR2 enhances synergistic immune surveillance in breast cancer

Open Date: 2017-04-01

Close Date: 2020-04-01

Articles (14)

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2025

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2022

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2022

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2021

Collaborators (5)

Mikala Egeblad

Johns Hopkins University

UNITED STATES

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DYLAN TAATJES

University of Colorado Boulder

UNITED STATES

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Jean Albrengues

INSERM Délégation régionale Provence Alpes Cote d'Azur et Corse

FRANCE

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Leemor Joshua-Tor

Professor and HHMI Investigator

UNITED STATES

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Lukas Kraehenbuehl

Chief

Kantonsspital Aarau AG

SWITZERLAND

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Xue-Yan He

Research Interests

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About

Recent Grants

Articles (14)

Neutrophils drive vascular occlusion, tumour necrosis and metastasis

Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma

Host response during unresolved urinary tract infection alters female mammary tissue homeostasis through collagen deposition and TIMP1

Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment

NETworking with cancer: The bidirectional interplay between cancer and neutrophil extracellular traps

Abstract 62: Untangling the connection between stress and metastatic breast cancer

T cell immunotherapies engage neutrophils to eliminate tumor antigen escape variants.

ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation

PTP1B inhibitors protect against acute lung injury and regulate CXCR4 signaling in neutrophils

OCA-T1 and OCA-T2 are coactivators of POU2F3 in the tuft cell lineage

A Bivalent Activatable Fluorescent Probe for Screening and Intravital Imaging of Chemotherapy-Induced Cancer Cell Death

Iraq/Afghanistan war lung injury reflects burn pits exposure

Caught in a Web: Emerging Roles of Neutrophil Extracellular Traps in Cancer

Activating a collaborative innate-adaptive immune response to control metastasis

Collaborators (5)

Mikala Egeblad

DYLAN TAATJES

Jean Albrengues

Leemor Joshua-Tor

Lukas Kraehenbuehl

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