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Liangguang Lin

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Assistant Professor

University of Virginia

United States

Research Interests

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Grant: Close

The novel role of SEL1L in cerebellar ataxia

Open Date: 2022-04-01

Close Date: 2023-04-01

Articles (12)

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2026

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2026

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2026

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2026

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2025

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2025

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2024

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2024

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2024

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2024

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2023

Year:

2023

Collaborators (7)

Shengyi Sun

Associate professor

University of Virginia

UNITED STATES

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Lulu Jiang

Assistant Professor

University of Virginia

UNITED STATES

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Carlos Lizama

Senior Scientist/Professional Researcher

University of California, San Francisco

UNITED STATES

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Ahmad Jomaa

Assistant Professor

University of Virginia

UNITED STATES

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Shuangcheng Wu

University of Texas Southwestern Medical Center

UNITED STATES

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Pengcheng Wang

Professor

Southern University of Science and Technology (SUSTech)

CHINA

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Rachel Reinert

Assistant Professor

University of Michigan

UNITED STATES

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Liangguang Lin

Research Interests

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Recent Grants

Articles (12)

A molecular switch in NAC prevents mitochondrial protein mistargeting by SRP

Functional rescue of a disease-linked ERAD pathway mutation via alternative splicing

SEL1L-HRD1 ER-associated degradation facilitates prohormone convertase 2 maturation and glucagon production in islet α cells

Structural basis and pathological implications of the dimeric OS9-SEL1L-HRD1 ERAD Core Complex

The endoplasmic reticulum-associated degradation machinery selectively degrades stress-induced TIN1 during stress recovery

Requirements for nuclear GRP78 transcriptional regulatory activities and interaction with nuclear GRP94

Genome-wide screens identify SEL1L as an intracellular rheostat controlling collagen turnover

Proteomic screens of SEL1L-HRD1 ER-associated degradation substrates reveal its role in glycosylphosphatidylinositol-anchored protein biogenesis

Publisher Correction: SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex

SEL1L-HRD1 interaction is required to form a functional HRD1 ERAD complex

Biallelic Cys141Tyr variant of SEL1L is associated with neurodevelopmental disorders, agammaglobulinemia and premature death

Hypomorphic variants of SEL1L-HRD1 ER-associated degradation are associated with neurodevelopmental disorders

Collaborators (7)

Shengyi Sun

Lulu Jiang

Carlos Lizama

Ahmad Jomaa

Shuangcheng Wu

Pengcheng Wang

Rachel Reinert

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