Liguo Wang

Associate Professor

Mayo Clinic Minnesota

United States

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Dr. Liguo Wang is an Associate Professor at Mayo Clinic in Minnesota, USA. His research interests focus on cancer biology, particularly in the areas of DNA damage response, epigenetic heterogeneity in liver disease, and the mechanisms of androgen receptor variants in prostate cancer. Dr. Wang's recent publications explore topics such as the immune response in CDK12-deregulated cancers and therapeutic strategies targeting TROP-2 in treatment-resistant prostate cancer.

Articles (17)

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2025

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2022

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2021

Collaborators (6)

housheng hansen he

Professor

CANADA

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Haojie Huang

Mayo Clinic College of Medicine and Science

UNITED STATES

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Daniel Hollern

Assistant Professor

Salk Institute for Biological Studies

UNITED STATES

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Dhanpat Jain

Yale University

UNITED STATES

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Erika Heninger

University of Wisconsin-Madison

UNITED STATES

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Thai Ho

Associate Professor

Medical University of South Carolina

UNITED STATES

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Liguo Wang

Research Interests

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Articles (17)

DNA2 protein destruction dictates DNA hyperexcision, cGAS–STING activation, and innate immune response in CDK12-deregulated cancers

SNP rs9364554 Modulates Androgen Receptor Binding and Drug Response in Prostate Cancer

Epigenetic heterogeneity hotspots in human liver disease progression

Identify Non-mutational p53 Functional Deficiency in Human Cancers

Expression and Therapeutic Targeting of TROP-2 in Treatment-Resistant Prostate Cancer

Publisher Correction: Reference-guided search for open reading frames

Gain-of-function mutant p53 together with ERG proto-oncogene drive prostate cancer by beta-catenin activation and pyrimidine synthesis

Androgen receptor variants confer castration resistance in prostate cancer by counteracting antiandrogen-induced ferroptosis

Reference-guided search for open reading frames

Cobind: quantitative analysis of the genomic overlaps

A lncRNA from the FTO locus acts as a suppressor of the m<sup>6</sup>A writer complex and p53 tumor suppression signaling

Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome

SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-β-independent manner

CYCLIN K down-regulation induces androgen receptor gene intronic polyadenylation, variant expression and PARP inhibitor vulnerability in castration-resistant prostate cancer

Retinoblastoma protein as an intrinsic BRD4 inhibitor modulates small molecule BET inhibitor sensitivity in cancer

SPOP mutation induces replication over-firing by impairing Geminin ubiquitination and triggers replication catastrophe upon ATR inhibition

FOXA1 overexpression suppresses interferon signaling and immune response in cancer

Collaborators (6)

housheng hansen he

Haojie Huang

Daniel Hollern

Dhanpat Jain

Erika Heninger

Thai Ho

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