Thai Ho

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Associate Professor

Medical University of South Carolina

United States

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About

Dr. Thai Ho is an Associate Professor at the Medical University of South Carolina, USA. His research focuses on the mechanisms of ferroptosis in cancer, cancer-associated macrophages, and the roles of epigenetic modifications in renal cell carcinoma. Recent publications include studies on the clinical utility of phagocytic cancer macrophages and the impact of SETD2 loss on tumor progression and treatment response.

Recent Grants

Grant: Open

Synthetic Lethal Targeting of SETD2 in Renal Cell Carcinoma

Open Date: 2023-02-01

Close Date: 2028-01-31

Grant: Open

Defining Novel Cardiovascular Mechanisms For TKI Induced Excitability

Open Date: 2022-09-01

Close Date: 2027-08-31

Grant: Close

Identifying and Targeting Epigenetic Vulnerabilities in the Histone H3 Lysine 36 Methylation Axis in Renal Cell Cancer

Open Date: 2021-09-30

Close Date: 2024-09-30

Grant: Close

Discover and Analyze Germline-Somatic Interactions in Cancer

Open Date: 2021-09-01

Close Date: 2024-08-31

Grant: Close

Hypoxia and Remodeling of Energy Metabolism in Renal Cell Carcinoma

Open Date: 2020-09-30

Close Date: 2022-09-29

Articles (16)

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2022

Collaborators (4)

Liguo Wang

Associate Professor

Mayo Clinic Minnesota

UNITED STATES

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Douglas F. Lake

Arizona State University

UNITED STATES

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Alan Haruo Bryce

Chief Clinical Officer

City of Hope

UNITED STATES

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Raymond Bergan

University of Nebraska Medical Center

UNITED STATES

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Thai Ho

Research Interests

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About

Recent Grants

Articles (16)

Targeting FSP1 to induce ferroptosis in chromophobe renal cell carcinoma.

Phenotyping and Clinical Utility of Phagocytic Polyploid Giant Cancer Macrophages in Blood.

SETD2 loss-of-function uniquely sensitizes cells to epigenetic targeting of NSD1-directed H3K36 methylation.

Deciphering the interplay between SETD2 mediated H3K36me3 and RNA N6-methyladenosine in clear cell renal cell carcinoma (ccRCC).

A method for screening functional anti-Treg antibodies using a Treg-like cell line.

Extensive intratumor regional epigenetic heterogeneity in clear cell renal cell carcinoma targets kidney enhancers and is associated with poor outcome

SETD2 loss in renal epithelial cells drives epithelial-to-mesenchymal transition in a TGF-β-independent manner

Cancer Associated Macrophage-like Cells Are Prognostic for Highly Aggressive Prostate Cancer in Both the Non-Metastatic and Metastatic Settings

Performing Automatic Identification and Staging of Urothelial Carcinoma in Bladder Cancer Patients Using a Hybrid Deep-Machine Learning Approach

Development of tandem antigen capture ELISAs measuring QSOX1 isoforms in plasma and serum.

Generation and characterization of a monoclonal antibody that binds to Galectin-1.

Cancer associated macrophage-like cells in metastatic renal cell carcinoma predicts for poor prognosis and tracks treatment response in real time.

Characterization of cutaneous adverse events to enfortumab vedotin: A retrospective case-control study.

Differential impact of tumor suppressor gene (TP53, PTEN, RB1) alterations and treatment outcomes in metastatic, hormone-sensitive prostate cancer

The impact of genetic aberrations on response to radium-223 treatment for castration-resistant prostate cancer with bone metastases.

Intracellular Signaling Pathways Mediating Tyrosine Kinase Inhibitor Cardiotoxicity.

Collaborators (4)

Liguo Wang

Douglas F. Lake

Alan Haruo Bryce

Raymond Bergan

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