Lihua Zhu

Professor and Head of Bioinformatics Core

University of Massachusetts Chan Medical School

United States

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About

Professor Lihua Zhu is the Head of the Bioinformatics Core at the University of Massachusetts Medical School, USA. Her research focuses on bioinformatics methods for analyzing cellular and genomic data, including studies on phosphorylation dynamics, sphingolipid synthesis, and genome stability. Recent publications highlight her contributions to understanding cancer therapeutics and RNA sequencing methodologies.

Articles (18)

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2025

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2022

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2022

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2021

Collaborators (9)

Olga Ponomarova

Assistant Professor

University of New Mexico

UNITED STATES

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Shunqing Liang

Assistant Professor

University of Minnesota

UNITED STATES

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Stefano Santaguida

Associate Professor

University of Milan

ITALY

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Pranam Chatterjee

Assistant Professor

University of Pennsylvania

UNITED STATES

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Wen Wang

University of Minnesota

UNITED STATES

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Lei Huang

Assistant Professor

UMass Memorial Medical Center

UNITED STATES

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Erik J. Sontheimer

University of Massachusetts Chan Medical School

UNITED STATES

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Jason Kim

Professor

University of Massachusetts Chan Medical School

UNITED STATES

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Namgyu Lee

University of Massachusetts Chan Medical School

UNITED STATES

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Lihua Zhu

Research Interests

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About

Articles (18)

Dynamic phosphorylation of Hcm1 promotes fitness in chronic stress

Sphingolipid synthesis maintains nuclear membrane integrity and genome stability during cell division

C-COUNT: a convolutional neural network–based tool for automated scoring of erythroid colonies

The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

InPAS: An R/Bioconductor Package for Identifying Novel Polyadenylation Sites and Alternative Polyadenylation from Bulk RNA-seq Data

CleanUpRNAseq: An R/Bioconductor Package for Detecting and Correcting DNA Contamination in RNA-Seq Data

A nutrient responsive lipase mediates gut-brain communication to regulate insulin secretion in Drosophila

Genome-wide profiling of prime editor off-target sites in vitro and in vivo using PE-tag

Therapeutic blocking of VEGF binding to neuropilin-2 diminishes PD-L1 expression to activate antitumor immunity in prostate cancer

Phosphosite Scanning reveals a complex phosphorylation code underlying CDK-dependent activation of Hcm1

Disruption of sugar nucleotide clearance is a therapeutic vulnerability of cancer cells.

Repression of essential cell cycle genes increases cellular fitness

A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis

Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors

LONP-1 and ATFS-1 sustain deleterious heteroplasmy by promoting mtDNA replication in dysfunctional mitochondria

Genome-wide detection of CRISPR editing in vivo using GUIDE-tag

O-linked α2,3 sialylation defines stem cell populations in breast cancer

EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis

Collaborators (9)

Olga Ponomarova

Shunqing Liang

Stefano Santaguida

Pranam Chatterjee

Wen Wang

Lei Huang

Erik J. Sontheimer

Jason Kim

Namgyu Lee

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