Louis Lambrechts

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Research Director and Unit Head

Institut Pasteur

France

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About

Louis Lambrechts is a Research Director and Unit Head at the Institut Pasteur in France. His research primarily focuses on the dynamics and evolution of transposable elements in mosquito genomes, as well as the interaction between mosquito vectors and viruses, including studies on dengue and Zika viruses. He has recently published articles examining the genetic factors influencing Aedes aegypti’s susceptibility to viral infections and the role of environmental variables in vector-borne disease transmission.

Recent Grants

Grant: Close

METHODS FOR MEASURING NATURAL DENGUE TRANSMISSION FROM HUMANS TO MOSQUITOES

Open Date: 2013-05-23

Close Date: 2015-04-30

Grant: Close

METHODS FOR MEASURING NATURAL DENGUE TRANSMISSION FROM HUMANS TO MOSQUITOES

Open Date: 2013-05-23

Close Date: 2015-04-30

Articles (19)

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2025

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2022

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2021

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2021

Collaborators (8)

Sébastian Lequime

Assistant Professor

Rijksuniversiteit Groningen

NETHERLANDS

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Nerea Irigoyen

University of Cambridge

UNITED KINGDOM

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Samia Elfekih

University of Melbourne

AUSTRALIA

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Jacob Koella

Professor

University of Neuchâtel

SWITZERLAND

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Emilie Giraud

Institut Pasteur

FRANCE

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Diego Ayala

University of Montpellier

FRANCE

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Alexander Khromykh

Professor

University of Queensland

AUSTRALIA

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Margus Varjak

UNITED KINGDOM

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Louis Lambrechts

Research Interests

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About

Recent Grants

Articles (19)

Thermal adaptation in Aedes aegypti does not constrain temperature-sensitive growth of bacteria or dengue virus

Adaptive genomic signatures of globally invasive populations of the yellow fever mosquito Aedes aegypti

Dynamics and evolution of transposable elements in mosquito genomes

Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants.

Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes.

Decoding mosquito–virus interactions: from classical genetics to multi-omics

Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti.

Arbovirus impact on mosquito behavior: the jury is still out

The role of vector population variation and climate in Zika virus transmission patterns in Africa: a modelling study.

Zika viruses encode 5' upstream open reading frames affecting infection of human brain cells.

Differential intra-host infection kinetics in Aedes aegypti underlie superior transmissibility of African relative to Asian Zika virus

Direct mosquito feedings on dengue-2 virus-infected people reveal dynamics of human infectiousness

Does arbovirus emergence in humans require adaptation to domestic mosquitoes?

Mutational analysis of Aedes aegypti Dicer 2 provides insights into the biogenesis of antiviral exogenous small interfering RNAs

Larval habitat determines the bacterial and fungal microbiota of the mosquito vector <i>Aedes aegypti</i>

Enhanced mosquito vectorial capacity underlies the Cape Verde Zika epidemic

Yearly variations of the genetic structure of Aedes aegypti (Linnaeus) (Diptera: Culicidae) in the Philippines (2017-2019).

Mosquito‐bacteria interactions during larval development trigger metabolic changes with carry‐over effects on adult fitness

Potential role of vector-mediated natural selection in dengue virus genotype/lineage replacements in two epidemiologically contrasted settings.

Collaborators (8)

Sébastian Lequime

Nerea Irigoyen

Samia Elfekih

Jacob Koella

Emilie Giraud

Diego Ayala

Alexander Khromykh

Margus Varjak

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