Luca Scorrano

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University of Padua

Italy

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Recent Grants

Grant: Close

Extending the Optic atrophy 1 dependent cristae remodeling: from models to a therapy of autosomal dominant optic atrophy

Open Date: 2015-10-01

Close Date: 2018-09-01

Grant: Close

Targeting autophagy to treat Cardiovascular Diseases

Open Date: 2015-10-01

Close Date: 2020-09-01

Grant: Close

Targeting Opa1-dependent mitochondrial cristae remodeling to enhance cancer cell death

Open Date: 2015-01-01

Close Date: 2017-12-01

Grant: Close

MitCare-2

Open Date: 2014-10-01

Close Date: 2017-09-01

Grant: Close

Balanced ubiquitination and deubiquitination of MFN2 in the regulation of the ER-mitotether: role of Parkin and its opposing DUB in the onset of PD

Open Date: 2014-07-01

Close Date: 2015-06-01

Articles (18)

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2024

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2023

Collaborators (28)

Nirmal Robinson

University of South Australia

AUSTRALIA

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Tatiana Varanita

Assistant Professor

University of Padua

ITALY

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Markus Rehm

GERMANY

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Shengjie Lu

Asst Professor

Duke-NUS Medical School

SINGAPORE

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Ivano Amelio

Professor & Chair

University of Konstanz

GERMANY

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Rune Busk Damgaard

Technical University of Denmark

DENMARK

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Kurt Engeland

Professor

Leipzig University

GERMANY

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Dmitri V. Krysko

Ghent University

BELGIUM

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David Sebastián

Assistant Professor

University of Barcelona

SPAIN

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Maria Andrea Desbats

Assistant Professor

University of Padua

ITALY

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Marta Giacomello

Associate Professor

Università degli Studi di Roma Tor Vergata Dipartimento di Biologia

ITALY

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Chiaki Takahashi

Kanazawa University

JAPAN

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Jacqueline Vanderluit

Professor

Memorial University of Newfoundland

CANADA

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Francesco Di Virgilio

Professor

University of Ferrara

ITALY

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Jean‐Ehrland Ricci

Université Côte d'Azur

FRANCE

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Derek Hausenloy

University College London

UNITED KINGDOM

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Camilla Bean

University of Udine

ITALY

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Marc Diederich

Seoul National University

SOUTH KOREA

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Luca Persano

University of Padova

ITALY

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David Pereira

Assistant Professor

University of Porto

PORTUGAL

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Susumu Kohno

JAPAN

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Daniel Murphy

Professor of Lung Cancer & Mesothelioma

University of Glasgow

UNITED KINGDOM

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John W. Elrod

Lewis Katz School of Medicine at Temple University

UNITED STATES

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Pilar Aparicio

Professora asociada

University of Barcelona

SPAIN

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Albert Quintana

Associate Professor

University of Barcelona

SPAIN

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María Isabel Hernández-Alvarez

Associate Professor and Group Leader

University of Barcelona

SPAIN

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Cristina Muñoz-Pinedo

Institut d'Investigacions Biomèdiques de Barcelona

SPAIN

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John M. Abrams

Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Luca Scorrano

Research Interests

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Recent Grants

Articles (18)

A RalA between high-fat diet and mitochondrial shape

Activation of Ca<sup>2+</sup> phosphatase Calcineurin regulates Parkin translocation to mitochondria and mitophagy in flies

The interplay between mitochondrial dynamics and autophagy: From a key homeostatic mechanism to a driver of pathology

Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy (Cell Death &amp; Disease, (2022), 13, 4, (398), 10.1038/s41419-022-04741-9)

Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria

Apoptotic cell death in disease—Current understanding of the NCCD 2023

High-Throughput Microscopy Analysis of Mitochondrial Membrane Potential in 2D and 3D Models

Dysfunctional mitochondria accumulate in a skeletal muscle knockout model of Smn1, the causal gene of spinal muscular atrophy

A Novel Benchtop Device for Efficient and Simple Purification of Cytokines, Growth Factors and Stem Cells from Adipose Tissue

Determinants and outcomes of mitochondrial dynamics

Inhibition of the mitochondria-shaping protein Opa1 restores sensitivity to Gefitinib in a lung adenocarcinomaresistant cell line

LDLs take a shortcut to mitochondria

Mind the GAP(43) for mitochondria transfer to glioblastomas

Mitochondrial cristae: lung cancer metabolism architects

OPA1 drives macrophage metabolism and functional commitment via p65 signaling

Targeting mitochondrial shape: at the heart of cardioprotection

IL-12/15/18-induced cell death and mitochondrial dynamics of human NK cells

The inhibition of inner mitochondrial fusion in hepatocytes reduces non-alcoholic fatty liver and improves metabolic profile during obesity by modulating bile acid conjugation

Collaborators (28)

Nirmal Robinson

Tatiana Varanita

Markus Rehm

Shengjie Lu

Ivano Amelio

Rune Busk Damgaard

Kurt Engeland

Dmitri V. Krysko

David Sebastián

Maria Andrea Desbats

Marta Giacomello

Chiaki Takahashi

Jacqueline Vanderluit

Francesco Di Virgilio

Jean‐Ehrland Ricci

Derek Hausenloy

Camilla Bean

Marc Diederich

Luca Persano

David Pereira

Susumu Kohno

Daniel Murphy

John W. Elrod

Pilar Aparicio

Albert Quintana

María Isabel Hernández-Alvarez

Cristina Muñoz-Pinedo

John M. Abrams

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Correction: Cisplatin resistance can be curtailed by blunting Bnip3-mediated mitochondrial autophagy (Cell Death & Disease, (2022), 13, 4, (398), 10.1038/s41419-022-04741-9)