Lucie Cahlikova

Charles University

Czech Republic

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Articles (11)

Innovative chemotype design provided 41 novel h BChE inhibitors. CNS availability was predicted using the BBB score. Potent derivatives showed favorable drug-like properties and acceptable safety profiles in SH-SY5Y and HepG2 cells.

Year:

2024

Year:

2023

Year:

2023

Year:

2022

Year:

2022

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Collaborators (16)

Milan Pour

Charles University, Faculty of Pharmacy in Hradec Kralove

CZECH REPUBLIC

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Radim Havelek

Charles University

CZECH REPUBLIC

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Franz Bucar

Graz University of Technology

AUSTRIA

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Monika Schmidt

Assistant professor

University of Hradec Kralove, Faculty of Science

CZECH REPUBLIC

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Jan Korabecny

National Institute of Mental Health

CZECH REPUBLIC

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Miguel Prudêncio

Universidade de Aveiro

PORTUGAL

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Jana Maříková

assistant professor

Charles University

CZECH REPUBLIC

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Darja Koutova

Charles University

CZECH REPUBLIC

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Přemysl Mladěnka

Charles University

CZECH REPUBLIC

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Kateřina Breiterová

postdoc, assistant professor

Charles University, Faculty of Pharmacy in Hradec Kralove

CZECH REPUBLIC

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Milan Malaník

Masaryk University

CZECH REPUBLIC

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Rudolf Vrabec

Assistant professor

Charles University, Faculty of Pharmacy in Hradec Kralove

CZECH REPUBLIC

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Martina Řezáčová

CZECH REPUBLIC

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Ondrej Soukup

University Hospital Hradec Králové

CZECH REPUBLIC

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Alejandro Carazo

Assistant Professor

Faculty of Pharmacy, Charles University

CZECH REPUBLIC

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Martina Hrabinova

University of Defence

CZECH REPUBLIC

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Lucie Cahlikova

Research Interests

Contact this professor

Articles (11)

Carltonine-derived compounds for targeted butyrylcholinesterase inhibition

Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro

Natural Alkaloids as Multi-Target Compounds towards Factors Implicated in Alzheimer’s Disease

Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents

Can Isoquinoline Alkaloids Affect Platelet Aggregation in Whole Human Blood?

Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity

Semisynthetic Derivatives of Selected Amaryllidaceae Alkaloids as a New Class of Antimycobacterial Agents

Pancracine, a Montanine-Type Amaryllidaceae Alkaloid, Inhibits Proliferation of A549 Lung Adenocarcinoma Cells and Induces Apoptotic Cell Death in MOLT-4 Leukemic Cells

Recent Progress on Biological Activity of Amaryllidaceae and Further Isoquinoline Alkaloids in Connection with Alzheimer’s Disease

Structure Elucidation and Cholinesterase Inhibition Activity of Two New Minor Amaryllidaceae Alkaloids

Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies

Collaborators (16)

Milan Pour

Radim Havelek

Franz Bucar

Monika Schmidt

Jan Korabecny

Miguel Prudêncio

Jana Maříková

Darja Koutova

Přemysl Mladěnka

Kateřina Breiterová

Milan Malaník

Rudolf Vrabec

Martina Řezáčová

Ondrej Soukup

Alejandro Carazo

Martina Hrabinova

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