Ondrej Soukup

University Hospital Hradec Králové

Czech Republic

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Articles (20)

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2025

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2021

Collaborators (18)

Tomáš Zárybnický

University of Helsinki

FINLAND

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Anetta Härtlova

University of Gothenburg

SWEDEN

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Marketa Chvojkova

National Institute of Mental Health

CZECH REPUBLIC

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Diego Muñoz-Torrero

Full Professor of Organic & Medicinal Chemistry

University of Barcelona

SPAIN

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Lucie Cahlikova

Charles University

CZECH REPUBLIC

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Monika Schmidt

Assistant professor

University of Hradec Kralove, Faculty of Science

CZECH REPUBLIC

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Jan Bures

CZECH REPUBLIC

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Jan Korabecny

National Institute of Mental Health

CZECH REPUBLIC

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Jana Maříková

assistant professor

Charles University

CZECH REPUBLIC

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Giuseppe Legname

Professor

Scuola Internazionale Superiore di Studi Avanzati

ITALY

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Lenka Pulkrabkova

Fakultní Nemocnice Hradec Králové

CZECH REPUBLIC

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Pavel Ryska

University Hospital Hradec Králové

CZECH REPUBLIC

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Martin Kuchar

VSB - Technical University of Ostrava

CZECH REPUBLIC

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Jaroslav Pejchal

Chief of toxicology group/associate professor

CZECH REPUBLIC

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Jan Bartáček

Assistant professor

University of Pardubice

CZECH REPUBLIC

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Aleš Šorf

University of Defence

CZECH REPUBLIC

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Orcan Alpar

Visiting Professor

University of Hradec Králové

CZECH REPUBLIC

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Martina Hrabinova

University of Defence

CZECH REPUBLIC

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Ondrej Soukup

Research Interests

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Articles (20)

Novel antitubercular agents based on 2,4-disubstituted 5-(aryl-2-ylmethyl)-5H-pyrrolo[3,2-d]pyrimidines

Glutamate utilization fuels rapid production of mitochondrial ROS in dendritic cells and drives systemic inflammation during tularemia

ADMET parameters of tacrine and its metabolites confirm unsuitability of Sus scrofa f. domestica model to study tacrine-associated hepatotoxicity

Revolutionizing tuberculosis treatment: Breakthroughs, challenges, and hope on the horizon

Prophylaxis by a reversible cholinesterase inhibitor and the NMDA receptor antagonist treatment as combinatorial countermeasure against nerve agent poisoning in mice model

Nakagami imaging and morphing for multiple sclerosis lesion volume estimation

DESIGN, CHEMICAL SYNTHESIS, AND IN VITRO EVALUATION OF NOVEL UNCHARGED CHOLINESTERASE REACTIVATOR

Pro-cognitive effects of dual tacrine derivatives acting as cholinesterase inhibitors and NMDA receptor antagonists

pH-induced morphological reversible transition from microparticles to vesicles for effective bacteria entrapment

The Effect of Tacrine on Functional Response of the Lower Oesophageal Sphincter Assessed by Endoscopic Luminal Impedance Planimetry in Experimental Pigs

A-agents, misleadingly known as “Novichoks”: a narrative review

Tacrine First-Phase Biotransformation and Associated Hepatotoxicity: A Possible Way to Avoid Quinone Methide Formation

Differentiated SH-SY5Y neuroblastoma cells as a model for evaluation of nerve agent-associated neurotoxicity

Neurotoxicity evoked by organophosphates and available countermeasures

Discovery of Dual Aβ/Tau Inhibitors and Evaluation of Their Therapeutic Effect on a Drosophila Model of Alzheimer’s Disease

Amaryllidaceae Alkaloids of Norbelladine-Type as Inspiration for Development of Highly Selective Butyrylcholinesterase Inhibitors: Synthesis, Biological Activity Evaluation, and Docking Studies

Cholinesterase Research

Heterocyclic Cathinones as Inhibitors of Kynurenine Aminotransferase II—Design, Synthesis, and Evaluation

Synthesis and Decontamination Effect on Chemical and Biological Agents of Benzoxonium-Like Salts

The Effect of Chemical Structure of OEG Ligand Shells with Quaternary Ammonium Moiety on the Colloidal Stabilization, Cellular Uptake and Photothermal Stability of Gold Nanorods

Collaborators (18)

Tomáš Zárybnický

Anetta Härtlova

Marketa Chvojkova

Diego Muñoz-Torrero

Lucie Cahlikova

Monika Schmidt

Jan Bures

Jan Korabecny

Jana Maříková

Giuseppe Legname

Lenka Pulkrabkova

Pavel Ryska

Martin Kuchar

Jaroslav Pejchal

Jan Bartáček

Aleš Šorf

Orcan Alpar

Martina Hrabinova

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