Lyubomir Chervenkov

Background Dental workers are exposed to allergenic materials in the workplace. Objectives To summarize patch test results in dental staff with work‐related dermatitis. Materials and Methods Cross‐sectional study of dental staff with dermatitis was conducted. Symptoms, clinical findings and results from patch tests with 40 dental allergens were summarized. Results Of 329 participants, 155 (47.1%) had at least one positive patch reaction. The highest frequency of positive reactions was observed for metals (38.6%), acrylics (7.3%) and additives in acrylic resins (3.6%). One hundred and eighty‐five (56.2%) participants were currently symptomatic; in this group, 79 (42.7%) had current dermatitis. Thirty‐eight patients had at least one positive patch test considered occupationally related to their current dermatitis. Conclusion Almost half of the dental staff with dermatitis had at least one positive patch test and approximately 12% had current occupational relevance of the allergens. Our results underscore the importance of patch testing in the evaluation of dental staff with dermatitis.

Background: This study aims to establish the value of apparent diffusion coefficient maps and other magnetic resonance sequences for active surveillance of prostate cancer. The study included 530 men with an average age of 66, who were under surveillance for prostate cancer. We have used multiparametric magnetic resonance imaging with subsequent transperineal biopsy (TPB) to verify the imaging findings. Results: We have observed a level of agreement of 67.30% between the apparent diffusion coefficient (ADC) maps, other magnetic resonance sequences, and the biopsy results. The sensitivity of the apparent diffusion coefficient is 97.14%, and the specificity is 37.50%. According to our data, apparent diffusion coefficient is the most accurate sequence, followed by diffusion imaging in prostate cancer detection. Conclusions: Based on our findings we advocate that the apparent diffusion coefficient should be included as an essential part of magnetic resonance scanning protocols for prostate cancer in at least bi-parametric settings. The best option will be apparent diffusion coefficient combined with diffusion imaging and T2 sequences. Further large-scale prospective controlled studies are required to define the precise role of multiparametric and bi-parametric magnetic resonance in the active surveillance of prostate cancer.