Marc Balmer

Aim This scoping review aimed to compile and evaluate clinical trials investigating digital applications in prosthetic diagnostics and treatment planning by assessing their clinical relevance and future potential. Methods Following the PCC‐framework for scoping reviews and combining the source of analysis (Population/P: “prosthodontics”), the technique of interest (Concept/C: “digital application”) and the field of interest (Context/C: “diagnostics”), a three‐pronged search strategy was applied in the database PubMed and Web of Science. Clinical trials (≥10 study participants, English/German) were considered until 2023‐03‐09. Reporting adhered to the PRISMA‐ScR statement. Results The search identified 520 titles, of which 18 full‐texts met the inclusion criteria for data extraction. The trials involved a total of 14,457 study participants and were mapped for prosthetic subdisciplines: fixed ( n = 9; 50%) and removable ( n = 4; 22%) prosthodontics, reconstructive dentistry in general ( n = 3; 17%), and temporo‐mandibular joint disorders ( n = 2; 11%). Data merging of medical format files, as DICOM+STL, was the dominant digital application ( n = 7; 39%); and virtual treatment simulation using digital smile design or digital wax‐up represented the most frequent prosthetic diagnostics ( n = 6; 33%). Conclusion This scoping review identified a relatively low number of clinical trials. The future potential of digital diagnostics appears to be mostly related to the subdiscipline of fixed prosthodontics, especially regarding virtual treatment simulation for communication with the patient and among dental professionals. Artificial intelligence emerged as a key technology in many of the identified studies. Further research in this area is needed to explore the capabilities of digital technologies in prosthetic diagnostics and treatment planning.