Marc Ouellette

Laval University

Canada

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Articles (9)

Year:

2024

Year:

2024

Year:

2024

Year:

2024

Two strains of Streptococcus pneumoniae , one expressing the methyltransferase Erm(B) and the other negative for erm (B), were selected for solithromycin resistance in vitro either with direct drug selection or with chemical mutagenesis followed by drug selection. We obtained a series of mutants that we characterized by next-generation sequencing.

Year:

2023

Year:

2023

Year:

2022

Year:

2021

Year:

2021

Collaborators (2)

Ismail Fliss

Full professor

Laval University

CANADA

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Sylvie Rebuffat

Professor

Muséum National d'Histoire Naturelle

FRANCE

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Marc Ouellette

Research Interests

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Articles (9)

Exploring the genetic basis of natural resistance to microcins

Holistic understanding of trimethoprim resistance in Streptococcus pneumoniae using an integrative approach of genome-wide association study, resistance reconstruction, and machine learning

CRISPR-Cas9 high-throughput screening to study drug resistance in Leishmania infantum

Long-Term Prevention of Arthroplasty Infections via Incorporation of Activated AgNbO3 Nanoparticles in PMMA Bone Cement

New Resistance Mutations Linked to Decreased Susceptibility to Solithromycin in Streptococcus pneumoniae Revealed by Chemogenomic Screens

Delving in folate metabolism in the parasite Leishmania major through a chemogenomic screen and methotrexate selection

Nondegradable Antimicrobial Silver-Based Perovskite

Decreased glutamate transport in acivicin resistant Leishmania tarentolae

Combined gene deletion of dihydrofolate reductase-thymidylate synthase and pteridine reductase in Leishmania infantum

Collaborators (2)

Ismail Fliss

Sylvie Rebuffat

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