Marcel Leist

University of Konstanz

Germany

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Articles (24)

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Collaborators (15)

Markus Brüll

University of Konstanz

GERMANY

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Jitao David Zhang

Assistent Lecturer

University of Basel

SWITZERLAND

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Susanne Hougaard Bennekou

Technical University of Denmark

DENMARK

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Ivano Amelio

Professor & Chair

University of Konstanz

GERMANY

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Katrin Madjar

Technische Universität Dortmund

GERMANY

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Paul Jennings

University of Amsterdam

NETHERLANDS

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Tamara Meijer

University of Amsterdam

NETHERLANDS

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Paul Walker

VP Head of Toxicology and Innovation Efficiency

UNITED KINGDOM

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giada carta

University of Amsterdam

NETHERLANDS

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Daniel Dietrich

Head of Department

University of Konstanz

GERMANY

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Anna Forsby

Associate Professor, senior scientist

Stockholm University

SWEDEN

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Gerhard Ecker

University Professor

Universität Wien

AUSTRIA

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Franziska Kappenberg

Technische Universität Dortmund

GERMANY

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Michael Basler

SWITZERLAND

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John Doe

Liverpool John Moores University

UNITED KINGDOM

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Marcel Leist

Research Interests

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Articles (24)

Interplay between genes and social environment: from epigenetics to precision medicine

Transcriptomic changes and mitochondrial toxicity in response to acute and repeat dose treatment with brequinar in human liver and kidney in vitro models

Mathematical modelling reveals compound-specific stress pathway activity

Lunatin-1 : a membrane-disruptive peptide isolated from Hadruroides lunatus scorpion venom with cytotoxicity against MDA-MB-231 breast cancer cell line

Testing Strategies for Metabolite-Mediated Neurotoxicity

Chemical and Biological Mechanisms Relevant to the Rescue of MG-132-Treated Neurons by Cysteine

Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism

Biology-inspired dynamic microphysiological system approaches to revolutionize basic research, healthcare and animal welfare

Developmental neurotoxicity (DNT) : A call for implementation of new approach methodologies for regulatory purposes: Summary of the 5th International Conference on DNT Testing

Guidance for Good In Vitro Reporting Standards (GIVReSt) : A draft for stakeholder discussion and background documentation

Preparation of Viable Human Neurites for Neurobiological and Neurodegeneration Studies

PathwayNexus: a tool for interactive metabolic data analysis

Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease

Transcriptome-based prediction of drugs, inhibiting cardiomyogenesis in human induced pluripotent stem cells

Structural Insights into Neonicotinoids and N-Unsubstituted Metabolites on Human nAChRs by Molecular Docking, Dynamics Simulations, and Calcium Imaging

Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells

Use of metabolic glycoengineering and pharmacological inhibitors to assess lipid and protein sialylation on cells

Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons

Definition of the Neurotoxicity-Associated Metabolic Signature Triggered by Berberine and Other Respiratory Chain Inhibitors

Analysis of health concerns not addressed by REACH for low tonnage chemicals and opportunities for new approach methodology

Optimization of the TeraTox Assay for Preclinical Teratogenicity Assessment

Specific Attenuation of Purinergic Signaling during Bortezomib-Induced Peripheral Neuropathy In Vitro

Generation of Human Nociceptor-Enriched Sensory Neurons for the Study of Pain-Related Dysfunctions

Distinct and Dynamic Transcriptome Adaptations of iPSC-Generated Astrocytes after Cytokine Stimulation

Collaborators (15)

Markus Brüll

Jitao David Zhang

Susanne Hougaard Bennekou

Ivano Amelio

Katrin Madjar

Paul Jennings

Tamara Meijer

Paul Walker

giada carta

Daniel Dietrich

Anna Forsby

Gerhard Ecker

Franziska Kappenberg

Michael Basler

John Doe

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