Paul Jennings

University of Amsterdam

Netherlands

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Articles (17)

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2024

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2024

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2024

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

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2022

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2022

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2022

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2021

Collaborators (17)

Olivia Klatt

Vrije Universiteit Amsterdam

NETHERLANDS

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Anja Wilmes

University of Amsterdam

NETHERLANDS

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Susanne Hougaard Bennekou

Technical University of Denmark

DENMARK

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Bas van de Velde

Vrije Universiteit Amsterdam

NETHERLANDS

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V. Chandrasekaran

University of Amsterdam

NETHERLANDS

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Maxime CULOT

Associate professor

Université d'Artois

FRANCE

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Alejandro Aguayo Orozco

Københavns Universitet

DENMARK

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Cleo TEBBY

Institut National de l'Environnement Industriel et des Risques

FRANCE

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Olivier Taboureau

Université Paris Cité

FRANCE

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Tamara Meijer

University of Amsterdam

NETHERLANDS

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Paul Walker

VP Head of Toxicology and Innovation Efficiency

UNITED KINGDOM

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Marcel Leist

University of Konstanz

GERMANY

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Julien Slagboom

University of Amsterdam

NETHERLANDS

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giada carta

University of Amsterdam

NETHERLANDS

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Jan N.M. Commandeur

Associate Professor

University of Amsterdam

NETHERLANDS

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Anna Forsby

Associate Professor, senior scientist

Stockholm University

SWEDEN

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Barbara Zdrazil

Universität Wien

AUSTRIA

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Paul Jennings

Research Interests

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Articles (17)

Characterization of Organic Anion and Cation Transport in Three Human Renal Proximal Tubular Epithelial Models

Development of a membrane-disruption assay using phospholipid vesicles as a proxy for the detection of cellular membrane degradation

Evaluation of the impact of iPSC differentiation protocols on transcriptomic signatures

Transcriptomic profile of human iPSC-derived podocyte-like cells exposed to a panel of xenobiotics

Protectiveness of NAM-based hazard assessment - which testing scope is required?

Capturing time-dependent activation of genes and stress-response pathways using transcriptomics in iPSC-derived renal proximal tubule cells

Transcriptomic-based evaluation of trichloroethylene glutathione and cysteine conjugates demonstrate phenotype-dependent stress responses in a panel of human in vitro models

Differentiation and Subculturing of Renal Proximal Tubular-like Cells Derived from Human iPSC

Exposure to cis- and trans-regioisomers of S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-glutathione result in quantitatively and qualitatively different cellular effects in RPTEC/TERT1 cells

Transcriptional landscape of mitochondrial electron transport chain inhibition in renal cells

Development of a high-throughput in vitro screening method for the assessment of cell-damaging activities of snake venoms

A quantitative AOP of mitochondrial toxicity based on data from three cell lines

Mapping the cellular response to electron transport chain inhibitors reveals selective signaling networks triggered by mitochondrial perturbation

An in vitro strategy using multiple human induced pluripotent stem cell-derived models to assess the toxicity of chemicals

"Commandeuring" Xenobiotic Metabolism

Hipsc-derived hepatocyte-like cells can be used as a model for transcriptomics-based study of chemical toxicity

Integrate mechanistic evidence from new approach methodologies (NAMs) into a read-across assessment to characterise trends in shared mode of action.

Collaborators (17)

Olivia Klatt

Anja Wilmes

Susanne Hougaard Bennekou

Bas van de Velde

V. Chandrasekaran

Maxime CULOT

Alejandro Aguayo Orozco

Cleo TEBBY

Olivier Taboureau

Tamara Meijer

Paul Walker

Marcel Leist

Julien Slagboom

giada carta

Jan N.M. Commandeur

Anna Forsby

Barbara Zdrazil

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