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Marco Cavaco

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Junior Researcher

Instituto Gulbenkian de Ciência

Portugal

Research Interests

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Professors in Portugal Professors in Pharmaceutical Chemistry Pharmaceutical Chemistry professors in Portugal

Recent Grants

Grant: Open

Exploring peptide-gold nanoparticle conjugation to improve the pharmacokinetic of anticancer peptides

Open Date: 2026-09-01

Close Date: 2028-08-31

Grant: Open

New multifunctional radiotheranostics based on supramolecular complexes

Open Date: 2025-01-01

Close Date: 2028-01-01

Grant: Close

Improving the brain penetration of PARPi through peptide conjugation – an efficacious and rapid solution to brain metastatic triple-negative breast cancer

Open Date: 2025-01-01

Close Date: 2026-07-01

Grant: Close

Development of new preclinical models of pediatric brain cancer – an effective and robust strategy to accelerate the development of new medicines

Open Date: 2024-08-01

Close Date: 2025-07-01

Grant: Close

Development of an organ-on-a-chip of triple-negative breast cancer metastases for drug screening (TNBC-BM model)

Open Date: 2024-01-01

Close Date: 2025-03-01

Articles (17)

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2023

Collaborators (22)

Vera Neves

Assistant Researcher

Universidade do Porto Faculdade de Medicina

PORTUGAL

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Ana S. Silva-Herdade

Auxiliar Professor

Universidade do Porto Faculdade de Medicina

PORTUGAL

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Filipa Mendes

Principal Investigator

Universidade de Aveiro

PORTUGAL

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José Manuel Pérez de la Lastra

Instituto de Agroquímica y Tecnología de Alimentos

SPAIN

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João Paulo Borges

Professor catedrático

Universidade de Aveiro

PORTUGAL

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Ana Salomé Veiga

Universidade de Aveiro

PORTUGAL

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Sandra N. Pinto

Universidade de Aveiro

PORTUGAL

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Frederico Aires da Silva

Assistant Professor and Principal Investigator

Faculty of Veterinary Medicine, University of Lisbon

PORTUGAL

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David Andreu

Universitat Pompeu Fabra

SPAIN

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Susanne Kossatz

Assistant Professor

Klinikum rechts der Isar der Technischen Universität München

GERMANY

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Joana Amaral

Assistant Professor

Universidade de Aveiro

PORTUGAL

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Catarina I. G Pinto

PosDoc

University of Zurich

SWITZERLAND

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Berta São Braz

Professora Associada com Agregação

Universidade de Lisboa Faculdade de Medicina Veterinária

PORTUGAL

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Antonio Jose Morales de la Nuez

Profesor Contratado Doctor

Universidad de Las Palmas de Gran Canaria

SPAIN

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Christopher Coxon

Heriot-Watt University

UNITED KINGDOM

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Lurdes Gano

Researcher

Universidade de Lisboa Instituto Superior Técnico

PORTUGAL

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Kehinde Ross

Reader in Molecular and Cellular Biology

Liverpool John Moores University

UNITED KINGDOM

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Joao Goncalves

Professor Catedrático

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Pierre-Yves Renard

Chercheur

University of Rouen

FRANCE

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Beatriz Traguedo Simões

Researcher

Instituto Gulbenkian de Ciência

PORTUGAL

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Jorge Jesus Correia

Professor Auxiliar com Agregação

Universidade de Lisboa Faculdade de Medicina Veterinária

PORTUGAL

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Francesca Giuntini

Professor of Medicinal Chemistry and Photoactive Therapeutics

Liverpool John Moores University

UNITED KINGDOM

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Marco Cavaco

Research Interests

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Recent Grants

Articles (17)

Multivalent peptides for blood–brain barrier translocation, cell penetration and microRNA-21 inhibition in glioblastoma

Comparative characterization of six teleost piscidins reveals distinct antimicrobial, antibiofilm and stability profiles

Chimeric peptide-based radiopharmaceuticals for glioblastoma imaging and therapy by targeting mHsp70 and enhancing BBB penetration

Linker Design in Antibody-Drug Conjugates: Balancing Stability and Drug Release

Optimizing magnetic hyperthermia for melanoma: the role of nanoparticle uptake inhibition

Antimigratory and Antiproliferative Effects of the Brain-Targeted Peptide Conjugate PepH3-vCPP2319 on Triple Negative Breast Cancer Cell Cultures

PepH3-modified nanocarriers for delivery of therapeutics across the blood-brain barrier

The Potential of Peptide-Based Inhibitors in Disrupting Protein–Protein Interactions for Targeted Cancer Therapy

The use of a selective, nontoxic dual-acting peptide for breast cancer patients with brain metastasis

vCPP2319 interacts with metastatic breast cancer extracellular vesicles (EVs) and transposes a human blood-brain barrier model

Molecular determinants for brain targeting by peptides: a meta-analysis approach with experimental validation

Non-toxicity of Plant Candicidal Peptides for Mammalian Cell Lines and Galleria mellonella Model to Improving Selectivity for Clinical Use

Quantitative Imaging of the Action of vCPP2319, an Antimicrobial Peptide from a Viral Scaffold, against Staphylococcus aureus Biofilms of a Clinical Isolate

Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells

Rabbit derived VL single-domains as promising scaffolds to generate antibody-drug conjugates

Panobinostat-loaded folate targeted liposomes as a promising drug delivery system for treatment of canine B-cell lymphoma

Structural and Biochemical Characterization of Three Antimicrobial Peptides from Capsicum annuum L. var. annuum Leaves for Anti-Candida Use

Collaborators (22)

Vera Neves

Ana S. Silva-Herdade

Filipa Mendes

José Manuel Pérez de la Lastra

João Paulo Borges

Ana Salomé Veiga

Sandra N. Pinto

Frederico Aires da Silva

David Andreu

Susanne Kossatz

Joana Amaral

Catarina I. G Pinto

Berta São Braz

Antonio Jose Morales de la Nuez

Christopher Coxon

Lurdes Gano

Kehinde Ross

Joao Goncalves

Pierre-Yves Renard

Beatriz Traguedo Simões

Jorge Jesus Correia

Francesca Giuntini

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