Marek Bajda

prof. dr hab.

Uniwersytet Jagiellonski Collegium Medicum

Poland

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Professor Marek Bajda is a faculty member at Uniwersytet Jagielloński w Krakowie Collegium Medicum in Poland. His research primarily focuses on the development of novel treatments for cancer and neurodegenerative diseases, with recent articles exploring areas such as mitochondrial targeted therapies, amino acid transporters, and multitarget-directed ligands. He is actively involved in structural studies and the search for effective drug candidates for conditions including Alzheimer's disease and autism spectrum disorder.

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Collaborators (21)

Anders Asbjørn Jensen

Professor

University of Copenhagen

DENMARK

Marek Bajda

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Articles (22)

Molecular Rotor‐Based NIR‐II TICTgens for Mitochondria‐Targeted Pyroptosis Induction and Multi‐Model Monitoring of Cancer Immunotherapy

Insight into the Structure of the Neutral Amino Acid Transporter B0AT2 Enabled the Discovery of Tiagabine as an Inhibitor

Cryo-EM structure of ACE2-SIT1 in complex with tiagabine

Structural Studies of the Taurine Transporter: A Potential Biological Target from the GABA Transporter Subfamily in Cancer Therapy

Reversed-phase thin-layer chromatography and ultra-performance liquid chromatography/mass spectrometry to estimate the drug likeness of phosphodiesterase 10A inhibitors with phthalimide core

4-Oxypiperidine Ethers as Multiple Targeting Ligands at Histamine H3 Receptors and Cholinesterases

Recent Advances in the Search for Effective Anti-Alzheimer’s Drugs

In silico structural studies on the vesicular neutral amino acid transporter NTT4 (SLC6A17)

Virtual Screening Approaches to Identify Promising Multitarget-Directed Ligands for the Treatment of Autism Spectrum Disorder

Rational Search for Betaine/GABA Transporter 1 Inhibitors─<i>In Vitro</i> Evaluation of Selected Hit Compound

New cyclopentaquinoline and 3,5-dichlorobenzoic acid hybrids with neuroprotection against oxidative stress for the treatment of Alzheimer’s disease

Guanidines: Synthesis of Novel Histamine H3R Antagonists with Additional Breast Anticancer Activity and Cholinesterases Inhibitory Effect

Taurine and Creatine Transporters as Potential Drug Targets in Cancer Therapy

Searching for new mTOR kinase inhibitors: Analysis of binding sites and validation of docking protocols

Discovery of novel multifunctional ligands targeting GABA transporters, butyrylcholinesterase, β-secretase, and amyloid β aggregation as potential treatment of Alzheimer's disease

The SLC6A15-SLC6A20 neutral amino acid transporter subfamily: functions, diseases, and their therapeutic relevance

Discovery of the First Highly Selective Antagonist of the GluK3 Kainate Receptor Subtype

Benzophenone Derivatives with Histamine H<sub>3</sub> Receptor Affinity and Cholinesterase Inhibitory Potency as Multitarget-Directed Ligands for Possible Therapy of Alzheimer’s Disease

Discovery of small molecule mechanistic target of rapamycin inhibitors as anti-aging and anti-cancer therapeutics

Analysis of Different Binding Modes for Tiagabine within the GAT-1 Transporter

Analysis of Binding Determinants for Different Classes of Competitive and Noncompetitive Inhibitors of Glycine Transporters

Multilevel virtual screening approach for discovery of thymidine phosphorylase inhibitors as potential anticancer agents

Collaborators (21)

Anders Asbjørn Jensen

Jadwiga Handzlik

Jacek Kabzinski

Marek Staszewski

Agnieszka Zagórska

Anna Wieckowska

Thor Møller

Tommy Johansen

Agnieszka Korga-Plewko

Zofia Chrienova

Tobias Werner

Magdalena Iwan

Petrine Wellendorph

Ewa Szymanska

Alba Espargaró

Katarzyna Kiec-Kononowicz

David Reiner-Link

Krzysztof Walczyński

Stefan Broer

Anders Skov Kristensen

Dorota Łażewska

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