Marek Ostaszewski
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Recent Grants
Grant: Close
Beyond COVID (Task lead)
Open Date: 2021-10-01
Close Date: 2024-09-01
Grant: Close
ImmUniverse: Transforming Diagnosis and Therapy of Immune-Mediated Diseases (Task lead)
Open Date: 2020-01-01
Close Date: 2025-01-01
Grant: Close
Biomarkers in Atopic Dermatitis and Psoriasis (Task lead)
Open Date: 2019-04-01
Close Date: 2024-03-01
Grant: Close
A Systems medicine approach to chronic inflammatory disease (Task lead)
Open Date: 2017-01-01
Close Date: 2022-09-01
Articles (11)
Exploration and comparison of molecular mechanisms across diseases using <scp>MINERVA</scp> Net
Protein function is often interpreted using molecular interaction diagrams, encoding roles a given protein plays in various molecular mechanisms. Information about disease‐related mechanisms can be inferred from disease maps, knowledge repositories containing manually constructed systems biology diagrams. Disease maps hosted on the Molecular Interaction Network VisuAlization (MINERVA) Platform are individually accessible through a REST API interface of each instance, making it challenging to systematically explore their contents. To address this challenge, we introduce the MINERVA Net web service, a repository of open‐access disease maps allowing users to publicly share minimal information about their maps. The MINERVA Net repository provides REST API endpoints of particular disease maps, which then can be individually queried for content. In this article, we describe the concept of MINERVA Net and illustrate its use by comparing proteins and their interactions in three different disease maps.
Year:
2023
Year:
2022
Collaborators (18)
Nick Dand
King’s College London
Robert Phair
Co-founder and Chief Science Officer
-
Anna Niarakis
Full Professor
Université Toulouse III - Paul Sabatier
David Marshall
University of York
Clare Mackay
University of Oxford
Enrico Glaab
-
Paola Di Meglio
King’s College London
Jan Hasenauer
Professor
Rheinische Friedrich-Wilhelms-Universität Bonn
Marc Gillespie
Professor
St. John's University
Felix Bruno Kleine Borgmann
-
Kenneth G. C. Smith
University of Cambridge
Rudi Balling
Senior Professor
University of Bonn
Susan Coort
University of Maastricht
ravi ramessur
King’s College London
Manuel Buttini
-
Tobias Czauderna
Professor
Hochschule Mittweida
Ralf Stephan
Institute for Globally Distributed Open Research and Education
Marvin Martens
University of Maastricht

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