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Maria Brito

Has grant

Full Professor

Universidade de Lisboa Faculdade de Farmácia

Portugal

Research Interests

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Professors in Portugal Professors in Cancer Biology Cancer Biology professors in Portugal

Recent Grants

Grant: Close

Pipeline for discovery of CDK4/6 inhibitors for metastatic breast cancer treatment

Open Date: 2022-04-01

Close Date: 2024-03-01

Grant: Close

Thioredoxin Arrest to Reduce Glioblastoma: Ethylmercury and Thimerosal to target Cancer

Open Date: 2018-09-01

Close Date: 2022-09-01

Grant: Close

Detect, prevent, eradicate: a multi-step strategy to abrogate brain metastasization of breast cancer

Open Date: 2018-09-01

Close Date: 2021-08-01

Grant: Close

Brain metastasization of breast cancer: from phenotype to pathways and signaling

Open Date: 2017-07-01

Close Date: 2019-06-01

Grant: Close

Brain metastasization of breast cancer: from phenotype to pathways and signaling

Open Date: 2017-07-01

Close Date: 2019-06-01

Articles (14)

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2026

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2021

Collaborators (12)

Juan Carlos Espín

RESEARCH PROFESSOR

Consejo Superior de Investigaciones Cientificas

SPAIN

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João Rocha

Universidade de Aveiro

PORTUGAL

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Rita C. Guedes

Universidade de Aveiro

PORTUGAL

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Antonio González-Sarrías

Research Scientist (investigador científico)

Centro de Edafología y Biología Aplicada del Segura

SPAIN

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Maria Manuela Gaspar

Investigadora Auxiliar

Universidade de Aveiro

PORTUGAL

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Juan Antonio Gimenez Bastida

Tenured Scientist

Consejo Superior de Investigaciones Cientificas

SPAIN

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Claudia Nunes dos Santos

Principal Investigator and Vice-Director for Research

Universidade de Aveiro

PORTUGAL

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Manuela Carvalheiro

Researcher

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Inês Figueira

Junior Researcher (6-year FCT-CEEC contract - BOOST_PD, ref:2022.00151.CEECIND)

Universidade Nova de Lisboa

PORTUGAL

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Ana Rita Vaz

Professor Auxiliar

Universidade de Lisboa Faculdade de Farmácia

PORTUGAL

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Rui Malhó

Associate Professor w/ habilitation

Universidade de Aveiro

PORTUGAL

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Margarida Silva

Assistant Professor

Faculty of Pharmacy, University of Lisbon

PORTUGAL

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Maria Brito

Research Interests

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Recent Grants

Articles (14)

Neuroprotective Effect of Physiological Circulating Phenolic Metabolites Against Oxidative Stress- and Neuroinflammation-Induced in Human Cellular Models

Metabolic Profiling of a Mediterranean-Inspired (Poly)phenol-Rich Mixture in the Brain: Perfusion Effect and In Vitro Blood–Brain Barrier Transport Validation

Urolithins and their phase II conjugates cross the blood–brain barrier and exert a stimulus-dependent anti-inflammatory effect on microglial cells by inhibiting NF-κB nuclear translocation

Unveiling the intricate dynamics of the interplay between triple-negative breast cancer cells and the blood-brain barrier endothelium

MEF2C and miR-194-5p: New Players in Triple Negative Breast Cancer Tumorigenesis

Abrogating Metastatic Properties of Triple-Negative Breast Cancer Cells by EGFR and PI3K Dual Inhibitors

Breast Cancer Brain Metastases: Implementation and Characterization of a Mouse Model Relying on Malignant Cells Inoculation in the Carotid Artery

Multi-Targeting Approach in Glioblastoma Using Computer-Assisted Drug Discovery Tools to Overcome the Blood–Brain Barrier and Target EGFR/PI3Kp110β Signaling

In Vitro Study of the Blood–Brain Barrier Transport of Natural Compounds Recovered from Agrifood By-Products and Microalgae

A Drug Screening Reveals Minocycline Hydrochloride as a Therapeutic Option to Prevent Breast Cancer Cells Extravasation across the Blood–Brain Barrier

Therapeutic Options in Neuro-Oncology

Behind Brain Metastases Formation: Cellular and Molecular Alterations and Blood–Brain Barrier Disruption

MicroRNAs and Extracellular Vesicles as Distinctive Biomarkers of Precocious and Advanced Stages of Breast Cancer Brain Metastases Development

Myocyte Enhancer Factor 2C as a New Player in Human Breast Cancer Brain Metastases

Collaborators (12)

Juan Carlos Espín

João Rocha

Rita C. Guedes

Antonio González-Sarrías

Maria Manuela Gaspar

Juan Antonio Gimenez Bastida

Claudia Nunes dos Santos

Manuela Carvalheiro

Inês Figueira

Ana Rita Vaz

Rui Malhó

Margarida Silva

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