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Mark Hatley

Has grant

Associate Member

St. Jude Children's Research Hospital

United States

Research Interests

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Recent Grants

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Mediators Of Arrested Differentiation In Pediatric Rhabdomyosarcoma

Open Date: 2021-02-01

Close Date: 2026-01-31

Grant: Close

Defining the non-myogenic origins of pediatric rhabdomyosarcoma

Open Date: 2017-04-05

Close Date: 2022-03-31

Grant: Close

Dissection of RAS pathway and PTEN loss in rhabdomyosarcoma

Open Date: 2016-11-01

Close Date: 2018-10-31

Grant: Close

Dissection of microRNA-21s role in non-small cell lung cancer

Open Date: 2011-09-01

Close Date: 2016-08-31

Grant: Close

Validation of microRNAs as valid targets in a pediatric sarcoma

Open Date: 2011-06-15

Close Date: 2014-01-21

Articles (20)

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2023

Collaborators (10)

Kelly M. Bailey

Associate Professor, Director AYA Translational Oncology

Mayo Clinic

UNITED STATES

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Yang Zhang

St. Jude Children's Research Hospital

UNITED STATES

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Juan Ortiz-Marquez

Senior Staff Scientist

Boston Children's Hospital

UNITED STATES

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John Choi

The University of Alabama

UNITED STATES

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Esther Obeng

Associate Professor

Emory University

UNITED STATES

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Silvia Pomella

RTT

University of Rome Tor Vergata

ITALY

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Rossella Rota

Group Leader

Ospedale Pediatrico Bambino Gesù

ITALY

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Jack Shern

Head, Tumor Evolution and Genomics Section

National Institutes of Health

UNITED STATES

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Gianni Bisogno

Docenti di ruolo di Ia fascia

University of Padova

ITALY

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Katie Hebron

Assistant Professor

Purdue University

UNITED STATES

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Mark Hatley

Research Interests

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Recent Grants

Articles (20)

Biological Advances and Current Challenges for Pediatric Rhabdomyosarcoma

Paediatric Therapeutic Development Workshop on rhabdomyosarcoma

RNA quality control enables antibiotic tolerance.

Pediatric sarcomas: challenges and opportunities

Elucidation of PAX3::FOXO1 tumor initiation mechanisms in human induced pluripotent stem cell models.

Insights into human alveolar rhabdomyosarcoma initiation using a human t(2;13) induced pluripotent stem cell model

Mechanism of PAX3::FOXO1 establishment of alveolar rhabdomyosarcoma cell state in human tumor initiation

Non-cell-autonomous tumor promotion in<i> DICER1</i> cancer predisposition

Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence (vol 44, 116339, 2025)

Generation of an iPSC-derived alveolar rhabdomyosarcoma cell line during directed endothelial differentiation

Developmental Heterogeneity of Rhabdomyosarcoma

Elucidation of PAX3::FOXO1 initiation mechanisms in human induced pluripotent stem cell models

Transdifferentiation of endothelial progenitor cells into rhabdomyosarcoma defined by hedgehog signaling competence

DICER1 cancer predisposition tumor promotion mediated non-cell autonomously via neutrophils and NETosis

Determining the genomic basis of PAX3-FOXO1 mediated transformation in rhabdomyosarcoma

Germline DICER1 loss promotes rhabdomyosarcoma via innate immune system

Histone lysine demethylase 4 family proteins maintain the transcriptional program and adrenergic cellular state of MYCN-amplified neuroblastoma

PAX3-FOXO1-induced transcriptional dysregulation in rhabdomyosarcoma

Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

PAX3-FOXO1 dictates myogenic reprogramming and rhabdomyosarcoma identity in endothelial progenitors.

Collaborators (10)

Kelly M. Bailey

Yang Zhang

Juan Ortiz-Marquez

John Choi

Esther Obeng

Silvia Pomella

Rossella Rota

Jack Shern

Gianni Bisogno

Katie Hebron

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