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Mark Plummer

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Head of Research and Innovation

Royal Adelaide Hospital

Australia

Research Interests

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Recent Grants

Grant: Open

MEGA-dose sodium ascorbate to reduce brain and kidney injury arising from Heart surgery (MEGA-HEART)

Open Date: 2025-04-01

Close Date: 2030-03-01

Grant: Close

Developing an instrumented large mammalian model of delayed cerebral ischaemia following subarachnoid haemorrhage.

Open Date: 2024-01-01

Close Date: 2025-01-01

Grant: Close

Validation of a novel PACS Biomarker and development of a diagnostic test

Open Date: 2023-01-01

Close Date:

Grant: Close

Do carriers of type 2 diabetes risk alleles in PAM have accelerated gastric emptying?

Open Date: 2023-01-01

Close Date: 2025-01-01

Grant: Close

Sickly sweet: managing high blood glucose during and post critical illness

Open Date: 2022-10-12

Close Date:

Articles (20)

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Collaborators (19)

Tongzhi Wu

University of Adelaide

AUSTRALIA

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Jerry R. Greenfield

Victor Chang Cardiac Research Institute

AUSTRALIA

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Amsterdam UMC Locatie VUmc

NETHERLANDS

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Jonathan Coles

Professor and Honorary Consultant

University of Cambridge

UNITED KINGDOM

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University of Melbourne

AUSTRALIA

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David Torpy

Senior Consultant/Head of Unit

University of Adelaide

AUSTRALIA

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Mark Plummer

Research Interests

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Recent Grants

Articles (20)

“There has to be an element of trust first”: An exploratory descriptive study of caring for Indigenous Peoples, family, and the wider community in Australian intensive care units

Reversal of cerebral ischaemia and hypoxia and of sickness behaviour by megadose sodium ascorbate in ovine Gram-negative sepsis. Response to Br J Anaesth 2026; 136: 781–2

An Update on Osmotherapy in Acute Brain Injury: Current and Emerging Strategies

Biochemical verification of tobacco use in ICU patients using point-of-care urinary cotinine

In Vivo Brain Deformation in a Sheep Model of Rapid Head Rotation

Early versus late surgical start times for on-pump cardiac surgery

Cardiovascular Outcomes of Perioperative Sodium‐Glucose Transporter 2 Inhibition in Cardiac Surgery Patients: An Open‐Label Randomized Pilot Study

The effects of sodium-glucose transporter 2 inhibition on cardiac surgery-associated acute kidney injury: An open-label randomized pilot study

Evidence from COVID-19 Patients and Murine Studies for a Continuing Trend Towards Targeting of Nasopharyngeal Ciliated Epithelial Cells by SARS-CoV-2 Omicron Sublineages

Precision Profiling of Disease Progression in Murine Models of Sepsis and Septic Shock

Cumulative Radiation Exposure Post Aneurysmal Subarachnoid Haemorrhage

Heterogeneity in the management of diabetic ketoacidosis in Australia: a national survey

In-hospital mortality in patients admitted to Australian intensive care units with COVID-19 between 2020 and 2024

Outcomes for older patients with subarachnoid haemorrhage who require admission to an Australian intensive care unit

Physiology and Pharmacology of Effects of GLP-1-based Therapies on Gastric, Biliary and Intestinal Motility

Cerebral Glucose Metabolism following TBI: Changes in Plasma Glucose, Glucose Transport and Alternative Pathways of Glycolysis—A Translational Narrative Review

Development of a quality indicator set for the optimal acute management of moderate to severe traumatic brain injury in the Australian context

A dose-adjusted, open-label, pilot study of the safety, tolerability, and pharmacokinetics of STC3141 in critically ill patients with sepsis

Clinical Consequences of Delayed Gastric Emptying With GLP-1 Receptor Agonists and Tirzepatide

Reversal of cerebral ischaemia and hypoxia and of sickness behaviour by megadose sodium ascorbate in ovine Gram-negative sepsis

Collaborators (19)

Tongzhi Wu

Jerry R. Greenfield

Ruth Van Lancker

Richard Young

Peter Cripton

Henning Hermanns

Jonathan Coles

Fatima Nasrallah

Jeroen Hermanides

Yugeesh R. Lankadeva

Caroline Phelan

Mahesh Umapathysivam

Abraham Hendrikus Hulst

Clive May

Julian Smith

Branka Grubor-Bauk

Adam Wells

Zhengyang Liu

David Torpy

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