Martijn Verdoes

Associate Professor

Radboud Universitair Medisch Centrum

Netherlands

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Dr. Martijn Verdoes is an Associate Professor at Radboud Universitair Medisch Centrum in the Netherlands. His research focuses on various aspects of immunology and cancer therapy, including the effects of biomaterials on immune cell behavior, antigen targeting in therapeutic vaccines, and mechanisms of immune resistance. Recent publications highlight his work on cytokine activity control, T cell activation, and the immune response to cancer-related treatments.

Articles (15)

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2025

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2022

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2022

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2022

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2021

Collaborators (6)

Sandra Heskamp

Radboud University Medical Center

NETHERLANDS

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Bouke Boekema

Head

Association of Dutch Burn Centres

NETHERLANDS

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Carl Figdor

University of Twente

NETHERLANDS

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Wilfred van IJcken

Erasmus University Rotterdam

NETHERLANDS

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Willeke F. Daamen

Radboud University Medical Center

NETHERLANDS

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Paul Kouwer

AssociateProf.

Radboud Universiteit Nijmegen

NETHERLANDS

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Martijn Verdoes

Research Interests

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Articles (15)

Effect of Hyaluronan in Collagen Biomaterials on Human Macrophages and Fibroblasts In Vitro

trans-Cyclooctene-caged-IL-1β immunocytokine-constructs ligated to unmodified nanobodies allow click-2-release-based control of cytokine activity

Semi‐Flexible Immunobrushes Facilitate Effective and Selective Expansion of Antigen‐Specific T Cells

pH and ROS Responsiveness of Polymersome Nanovaccines for Antigen and Adjuvant Codelivery: An In Vitro and In Vivo Comparison

Effect of Antigen Valency on Autoreactive B-Cell Targeting

Inhibition of CSF-1R and IL-6R prevents conversion of cDC2s into immune incompetent tumor-induced DC3s boosting DC-driven therapy potential.

PD-L1 checkpoint blockade promotes regulatory T cell activity that underlies therapy resistance

Controlling Antigen Fate in Therapeutic Cancer Vaccines by Targeting Dendritic Cell Receptors

Direct In Vivo Activation of T Cells with Nanosized Immunofilaments Inhibits Tumor Growth and Metastasis

Insights in the host response towards biomaterial-based scaffolds for cancer therapy.

CRISPR/Cas9-based Engineering of Immunoglobulin Loci in Hybridoma Cells.

Enzyme‐Activatable Chemokine Conjugates for In Vivo Targeting of Tumor‐Associated Macrophages

Enzyme‐Activatable Chemokine Conjugates for In Vivo Targeting of Tumor‐Associated Macrophages

Inhibitory prodrug mechanism for cysteine cathepsin-targeted self-controlled drug release.

Semiflexible Immunobrushes Induce Enhanced T Cell Activation and Expansion

Collaborators (6)

Sandra Heskamp

Bouke Boekema

Carl Figdor

Wilfred van IJcken

Willeke F. Daamen

Paul Kouwer

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