Martin Grootveld

Laser-activated tooth bleaching is discussed as a means to optimize results, while minimizing adverse side effects, but it lacks consensus in the scientific literature. Therefore, this systematic review aims to evaluate the protocols and outcomes of laser-activated vs. non-activated bleaching methods for safe and effective approaches. The PubMed, Cochrane, Scopus, ScienceDirect, and Google Scholar search engines, with the following MeSH terms and keywords: (bleaching OR whitening) AND laser AND (tooth OR dental OR enamel OR dentine), were used to identify human clinical trials and in vitro studies regarding laser-activated dental bleaching. After applying the keywords and additional filters, and inclusion and exclusion criteria, the final number of included articles was 19 clinical and 20 in vitro studies. Laser activation yielded no significant color improvement, but reduced gel contact time (10 min). Laser-activated bleaching required 24% less hydrogen peroxide (HP) concentration to achieve similar results. Additionally, there were no significant differences in terms of sensitivity and hard tissue alterations between the laser-activated and conventional groups. The benefits associated with laser-activated bleaching render it a compelling option. Nevertheless, a comprehensive evaluation of bleaching gels and activation protocols is imperative. Ultimately, this analysis provides clinical guidance pertaining to the facilitatory employment of laser irradiation.