Martin Horak

Czech Academy of Sciences, Institute of Experimental Medicine

Czech Republic

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Articles (10)

Year:

2023

Year:

2023

Year:

2023

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Collaborators (2)

Miloslav Korinek

Institute of Physiology

CZECH REPUBLIC

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Ladislav Vyklicky

Institute of Physiology CAS

CZECH REPUBLIC

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Martin Horak

Research Interests

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Articles (10)

Structure-Guided Design of N-Methylpropargylamino- Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease

Subunit-Dependent Surface Mobility and Localization of NMDA Receptors in Hippocampal Neurons Measured Using Nanobody Probes

The pathogenic N650K variant in the GluN1 subunit regulates the trafficking, conductance, and pharmacological properties of NMDA receptors

Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations

7-phenoxytacrine is a dually acting drug with neuroprotective efficacy in vivo

Pursuing the Complexity of Alzheimer's Disease: Discovery of Fluoren-9-Amines as Selective Butyrylcholinesterase Inhibitors and N-Methyl-d-Aspartate Receptor Antagonists

Specific pathogenic mutations in the M3 domain of the GluN1 subunit regulate the surface delivery and pharmacological sensitivity of NMDA receptors

Structure-activity relationships of dually-acting acetylcholinesterase inhibitors derived from tacrine on N-methyl-D-Aspartate receptors

The Extracellular Domains of GluN Subunits Play an Essential Role in Processing NMDA Receptors in the ER

Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission

Collaborators (2)

Miloslav Korinek

Ladislav Vyklicky

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