Miloslav Korinek

Institute of Physiology

Czech Republic

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Articles (8)

Year:

2024

Year:

2023

Year:

2022

Year:

2021

Year:

2021

Year:

2021

Year:

2020

Year:

2020

Collaborators (5)

Martin Horak

Czech Academy of Sciences, Institute of Experimental Medicine

CZECH REPUBLIC

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Ladislav Vyklicky

Institute of Physiology CAS

CZECH REPUBLIC

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Ales Balik

Institute of Physiology

CZECH REPUBLIC

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Jiří Černý

since 2017 Head of Laboratory of Structural Bioinformatics of Proteins

Czech Academy of Sciences

CZECH REPUBLIC

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Tereza Smejkalova

Institute of Physiology of the Czech Academy of Sciences

CZECH REPUBLIC

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Miloslav Korinek

Research Interests

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Articles (8)

Disease-associated nonsense and frame-shift variants resulting in the truncation of the GluN2A or GluN2B C-terminal domain decrease NMDAR surface expression and reduce potentiating effects of neurosteroids

Effects of Pregnanolone Glutamate and Its Metabolites on GABAA and NMDA Receptors and Zebrafish Behavior

Pregnane-based steroids are novel positive NMDA receptor modulators that may compensate for the effect of loss-of-function disease-associated GRIN mutations

Endogenous neurosteroids pregnanolone and pregnanolone sulfate potentiate presynaptic glutamate release through distinct mechanisms

Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity

Palmitoylation Controls NMDA Receptor Function and Steroid Sensitivity.

Site of Action of Brain Neurosteroid Pregnenolone Sulfate at the N-Methyl-D-Aspartate Receptor

Cholesterol modulates presynaptic and postsynaptic properties of excitatory synaptic transmission

Collaborators (5)

Martin Horak

Ladislav Vyklicky

Ales Balik

Jiří Černý

Tereza Smejkalova

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