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Martin Safo

Professor

Virginia Commonwealth University

United States

Has grant

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Research Interests

Pharmacology

50%

Biochemistry

20%

Sickle Cell Disease

30%

Endocannabinoid

30%

Antifungal Pharmacology

20%

Nitric Oxide

20%

Metabolic Biology

20%

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Recent Grants

Grant: Close

X-ray Crystallographic Data Collection System

Open Date: 2017-03-15

Close Date: 2018-03-14

Grant: Close

Hemoglobin Modifiers for Sickle Cell Disease Therapy

Open Date: 2014-07-11

Close Date: 2019-04-30

Articles13

The antisickling agent, 5‐hydroxymethyl‐2‐furfural: Other potential pharmacological applications

Article Link

Year:

2024

α-Glucosidase, butyrylcholinesterase and acetylcholinesterase inhibitory activities of phenolic compounds from Carthamus tinctorius L. flowers: In silico and in vitro studies

Article Link

Year:

2024

Incorporating valsartan in sesame oil enriched self-nanoemulsifying system-loaded liquisolid tablets to improve its bioavailability

Article Link

Year:

2023

Diminishing the Pathogenesis of the Food-Borne Pathogen Serratia marcescens by Low Doses of Sodium Citrate

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Year:

2023

Design, Synthesis, and Antisickling Investigation of a Thiazolidine Prodrug of TD-7 That Prolongs the Duration of Action of Antisickling Aromatic Aldehyde

Article Link

Year:

2023

Elucidating the Interaction between Pyridoxine 5′-Phosphate Oxidase and Dopa Decarboxylase: Activation of B6-Dependent Enzyme

Article Link

Year:

2022

Docking and Molecular Dynamic Investigations of Phenylspirodrimanes as Cannabinoid Receptor-2 Agonists

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Year:

2022

Integracides: Tetracyclic Triterpenoids from Fusarium sp.—Their 5-Lipoxygenase Inhibitory Potential and Structure–Activity Relation Using In Vitro and Molecular Docking Studies

Article Link

Year:

2022

Influences of Glimepiride Self-Nanoemulsifying Drug Delivery System Loaded Liquisolid Tablets on the Hypoglycemic Activity and Pancreatic Histopathological Changes in Streptozotocin-Induced Hyperglycemic Rats

Article Link

Year:

2022

Design, Synthesis, and Investigation of Novel Nitric Oxide (NO)-Releasing Aromatic Aldehyde as Drug Candidates for the Treatment of Sickle Cell Disease

Article Link

Year:

2022

Metabolic Reprogramming in Sickle Cell Diseases: Pathophysiology and Drug Discovery Opportunities

Article Link

Year:

2022

Anti-Quorum Sensing Activities of Gliptins against Pseudomonas aeruginosa and Staphylococcus aureus

Article Link

Year:

2022

Design, Synthesis, and Antisickling Investigation of a Nitric Oxide-Releasing Prodrug of 5HMF for the Treatment of Sickle Cell Disease

Article Link

Year:

2022

Collaborators6

El-Sayed Khafagy

SAUDI ARABIA

Khalid M. El-Say

SAUDI ARABIA

Piyusha Pagare

Research Assistant Professor

Virginia Commonwealth University

UNITED STATES

Tarek S. Ibrahim

SAUDI ARABIA

Tarek A. Ahmed

SAUDI ARABIA

Tim J. McMahon

Duke University Medical Center

UNITED STATES

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