Mascha Binder

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University Hospital Basel

Switzerland

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Recent Grants

Grant: Close

Evolutionäre ´dead-ends´ als Biomarker für Immun Checkpoint Blockade

Open Date: 2022-01-01

Close Date: 2025-01-01

Grant: Close

Phase 2 multicenter study investigating the tolerability and efficacy of UV1 vaccine in patients with recurrent or metastatic PD-L1 positive (CPS≥1) head and neck squamous cell carcinoma planned for first-line treatment with pembrolizumab

Open Date: 2021-01-01

Close Date: 2024-01-01

Grant: Close

A Phase II, randomized (1:1) open label study to assess the efficacy and safety of eltrombopag in combination with dexamethasone compared to dexamethasone, as first-line treatment in adult patients with newly diagnosed immune thrombocytopenia (ITP)

Open Date: 2020-01-01

Close Date: 2023-01-01

Grant: Close

TARC: Chemoradiotherapy phase 1 trial for patients with rectal cancer and liquid biopsy monitoring

Open Date: 2020-01-01

Close Date: 2024-01-01

Grant: Close

immunomonitor

Open Date: 2019-01-01

Close Date: 2021-01-01

Articles (20)

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Collaborators (17)

Javeed Iqbal

Professor,

University of Nebraska Medical Center

UNITED STATES

Mascha Binder

Research Interests

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Recent Grants

Articles (20)

Differential associations between SARS-CoV-2 infection, perceived burden of the pandemic and mental health in the German population-based cohort for digital health research

T-cell receptor architecture and clonal tiding provide insight into the transformation trajectory of peripheral T-cell lymphomas

A20 haploinsufficiency disturbs immune homeostasis and drives the transformation of lymphocytes with permissive antigen receptors

B cells expressing mutated IGHV1-69–encoded antigen receptors related to virus neutralization show lymphoma-like transcriptomes in patients with chronic HCV infection

Household transmission of Omicron variant of SARS-CoV-2 under conditions of hybrid immunity—a prospective study in Germany

Detection of disease-specific signatures in B cell repertoires of lymphomas using machine learning

The contribution of SARS-CoV-2 to the burden of acute respiratory infections in winter season 2022/2023: results from the DigiHero study

Trifluridine/tipiracil based chemoradiation in locally advanced rectal cancer - The phase I/II TARC trial

Insights into early recovery from Long COVID-results from the German DigiHero Cohort.

NKp44/HLA-DP-dependent regulation of CD8 effector T cells by NK cells

Association between virus variants, vaccination, previous infections, and post-COVID-19 risk

Pomalidomide combinations are a safe and effective option after daratumumab failure

T cell repertoire breadth is associated with the number of acute respiratory infections in the LoewenKIDS birth cohort.

First-line treatment of unresectable or metastatic HER2 positive esophagogastric adenocarcinoma: liquid biomarker analysis of the phase 2 INTEGA trial

SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters

Machine learning analysis of humoral and cellular responses to SARS-CoV-2 infection in young adults

Autoantigen-selected B cells are bystanders in spontaneous T cell-driven experimental autoimmune hepatitis.

Immune signatures in variant syndromes of primary biliary cholangitis and autoimmune hepatitis

Anxiety, depressive symptoms, and distress over the course of the war in Ukraine in three federal states in Germany.

Mental health in Germany in the first weeks of the Russo-Ukrainian war.

Collaborators (17)

Javeed Iqbal

Cornelia Gottschick

Johannes Herkel

Annamaria Brioli

Alexandra Title

Inken Hilgendorf

Meret Schmidhauser

Sandra Milena Bernal Ulloa

Silja Steinmann

Julia E. Vogt

Florian Heidel

Britta F. Zecher

Matthias Girndt

Maria Kalweit

Thomas Mueller

Alexandar Tzankov

Thomas Weber

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