Thomas Mueller

Martin Luther University Halle-Wittenberg

Germany

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Research Interests

Cell Biology

60%

Biochemistry

30%

Cancer Biology

60%

Multidrug Resistance

40%

Chemical Biology

40%

Cancer Therapy

30%

Crispr/cas9

30%

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Articles17

(Iso)quinoline amides derived from corosolic acid exhibit high cytotoxicity, and the potential for overcoming drug resistance in human cancer cells

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Year:

2024

Dehydroabietylamine-substituted trifluorobenzene sulfonamide rhodamine B hybrids as anticancer agents overcoming drug resistance.

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Year:

2024

Combination of Betulinic Acid Fragments and Carbonic Anhydrase Inhibitors—A New Drug Targeting Approach

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Year:

2024

F16 Hybrids Derived from Steviol or Isosteviol Are Accumulated in the Mitochondria of Tumor Cells and Overcome Drug Resistance

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Year:

2024

F16 Hybrids Derived from Steviol or Isosteviol Are Accumulated in the Mitochondria of Tumor Cells and Overcome Drug Resistance

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Year:

2024

Integrated Microarray-Based Data Analysis of miRNA Expression Profiles: Identification of Novel Biomarkers of Cisplatin-Resistance in Testicular Germ Cell Tumours

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Year:

2023

SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters

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Year:

2023

Palladium and Platinum Complexes of the Antimetabolite Fludarabine with Vastly Enhanced Selectivity for Tumour over Non-Malignant Cells

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Year:

2023

Luciferase Expressing Preclinical Model Systems Representing the Different Molecular Subtypes of Colorectal Cancer

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Year:

2023

Mitochondria-Targeting 1,5-Diazacyclooctane-Spacered Triterpene Rhodamine Conjugates Exhibit Cytotoxicity at Sub-Nanomolar Concentration against Breast Cancer Cells

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Year:

2023

Differential CMS-Related Expression of Cell Surface Carbonic Anhydrases IX and XII in Colorectal Cancer Models—Implications for Therapy

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Year:

2023

Targeted theranostics: Near-infrared triterpenoic acid-rhodamine conjugates as prerequisites for precise cancer diagnosis and therapy

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Year:

2023

Asiatic acid as a leading structure for derivatives combining sub-nanomolar cytotoxicity, high selectivity, and the ability to overcome drug resistance in human preclinical tumor models.

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Year:

2023

Differential CMS-Related Expression of Cell Surface Carbonic Anhydrases IX and XII in Colorectal Cancer Models-Implications for Therapy

Article Link

Year:

2023

Integrated Microarray-Based Data Analysis of miRNA Expression Profiles: Identification of Novel Biomarkers of Cisplatin-Resistance in Testicular Germ Cell Tumours

Article Link

Year:

2023

Imidazole Analogs of Vascular-Disrupting Combretastatin A-4 with Pleiotropic Efficacy against Resistant Colorectal Cancer Models

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Year:

2021

Intratumoral Distribution and pH-Dependent Drug Release of High Molecular Weight HPMA Copolymer Drug Conjugates Strongly Depend on Specific Tumor Substructure and Microenvironment

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Year:

2020

Collaborators8

Javeed Iqbal

Professor,

University of Nebraska Medical Center

UNITED STATES

Henrike Lucas

Martin Luther University Halle-Wittenberg

GERMANY

João Lobo

Lecturer in Pathology - Master degree in Medicine

Universidade do Porto Instituto de Ciências Biomédicas Abel Salazar

PORTUGAL

René Csuk

GERMANY

Matthias Bache

Martin Luther University Halle-Wittenberg

GERMANY

Mascha Binder

University Hospital Basel

SWITZERLAND

Viktor Brabec

Professor

Palacký University, Olomouc

CZECH REPUBLIC

Thomas Weber

GERMANY

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