Matteo Villa

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Assistant Professor

Medical University of Graz

Austria

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About

Matteo Villa is an Assistant Professor at the Medical University of Graz, Austria. His research primarily focuses on immunology and cellular metabolism, with recent articles exploring topics such as the metabolic checkpoints in hepatitis virus-specific CD8 + T cells and the role of adipose tissue in immune function. He investigates how metabolic rewiring and signaling pathways influence T cell function and differentiation.

Recent Grants

Grant: Close

Development of an intestine-specific anti-TNF antibody

Open Date: 2021-10-01

Close Date: 2022-09-01

Grant: Close

Single cell exploration of the adaptation of T cells to the intestinal microenvironement

Open Date: 2020-12-01

Close Date: 2022-09-01

Grant: Close

Metabolic adaptation of T cells to the intestinal microenvironment

Open Date: 2017-11-01

Close Date: 2019-10-01

Grant: Close

The role of aryl hydrocarbon receptor in B cell immunity

Open Date: 2011-10-01

Close Date: 2014-09-01

Articles (11)

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2023

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2023

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Collaborators (12)

Kathrin Schumann

Assistant Professor

Technical University of Munich

GERMANY

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Ryan Kyle

Sitryx Therapeutics

UNITED KINGDOM

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Peter Carmeliet

Aarhus University

DENMARK

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Andreas Wack

The Francis Crick Institute

UNITED KINGDOM

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Petya Apostolova

Assistant Professor of Experimental Hematology

University of Basel

SWITZERLAND

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Marcus Panning

GERMANY

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Stefania Crotta

The Francis Crick Institute

UNITED KINGDOM

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Oliver Gorka

University Medical Center Freiburg

GERMANY

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Ramon Klein Geltink

Assistant Professor

The University of British Columbia

CANADA

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Joerg Buescher

Head of Metabolomics Core Facility

Max Planck Institute of Immunobiology and Epigenetics

GERMANY

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David E Sanin

Assistant Professor

Johns Hopkins University

UNITED STATES

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Hauke Weiss

Trinity College Dublin

IRELAND

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Matteo Villa

Research Interests

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About

Recent Grants

Articles (11)

Repair of airway epithelia requires metabolic rewiring towards fatty acid oxidation

Phosphoinositide acyl chain saturation drives CD8+ effector T cell signaling and function

Enolase represents a metabolic checkpoint controlling the differential exhaustion programmes of hepatitis virus-specific CD8<sup>+</sup>T cells

Resident T H 2 cells orchestrate adipose tissue remodeling at a site adjacent to infection

An LKB1-mitochondria axis controls T<sub>H</sub>17 effector function.

Intracellular infection and immune system cues rewire adipocytes to acquire immune function

Fever supports CD8+ effector T cell responses by promoting mitochondrial translation

Research Techniques Made Simple: Profiling Cellular Energy Metabolism

Polyamine metabolism is a central determinant of helper T cell lineage fidelity.

Glucose makes T<sub>reg</sub> lose their temper.

How to make a better T cell: in vivo CRISPR screens have some answers.

Collaborators (12)

Kathrin Schumann

Ryan Kyle

Peter Carmeliet

Andreas Wack

Petya Apostolova

Marcus Panning

Stefania Crotta

Oliver Gorka

Ramon Klein Geltink

Joerg Buescher

David E Sanin

Hauke Weiss

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