Matthew Vander Heiden

Massachusetts Institute of Technology

United States

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Articles (18)

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2025

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2021

Collaborators (8)

Rebecca Lee

The University of Manchester

UNITED KINGDOM

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Giovanni Parmigiani

Professor

Dana-Farber Cancer Institute

UNITED STATES

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Jae-Seok Roe

Associate Professor

Yonsei University

SOUTH KOREA

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Peter Sorger

Otto Krayer Professor of Systems Pharmacology

Harvard Medical School

UNITED STATES

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Alicia Darnell

Duke University

UNITED STATES

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SABRINA SPENCER

University of Colorado Boulder

UNITED STATES

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Thomas Cox

Laboratory Head (Faculty) - Matrix & Metastasis

Garvan Institute of Medical Research

AUSTRALIA

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Steffen Rickelt

Massachusetts Institute of Technology

UNITED STATES

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Matthew Vander Heiden

Research Interests

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Articles (18)

Histone chaperones coupled to DNA replication and transcription control divergent chromatin elements to maintain cell fate

Effects of Aging on Glucose and Lipid Metabolism in Mice

Understanding the Warburg Effect in Cancer

Why do patients with cancer die?

A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments

Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis

The bidirectional relationship between metabolism and cell cycle control

Approaches to Study Tumor Metabolism in Mice

Cells use multiple mechanisms for cell-cycle arrest upon withdrawal of individual amino acids

GOT2 consider the tumor microenvironment

Nucleotide imbalance decouples cell growth from cell proliferation

Interactions with stromal cells promote a more oxidized cancer cell redox state in pancreatic tumors

Gene Expression Pathways in Prostate Tissue Associated with Vigorous Physical Activity in Prostate Cancer

Low glycaemic diets alter lipid metabolism to influence tumour growth

Patient-Derived Xenografts to Study Cancer Metabolism: When Does X Mark the Spot?

Suppression of pancreatic ductal adenocarcinoma growth and metastasis by fibrillar collagens produced selectively by tumor cells

Mitochondrial NADPH is a pro at Pro synthesis

The metabolic landscape of RAS-driven cancers from biology to therapy

Collaborators (8)

Rebecca Lee

Giovanni Parmigiani

Jae-Seok Roe

Peter Sorger

Alicia Darnell

SABRINA SPENCER

Thomas Cox

Steffen Rickelt

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