Matthias E. Liechti

Professor

University of Basel

Switzerland

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About

Matthias E. Liechti is a Professor at Universitätsspital Basel in Switzerland. His research areas encompass pharmacokinetics and pharmacodynamics, with a particular focus on psychoactive substances, including MDMA, LSD, and mescaline. He has authored several recent articles examining the effects and therapeutic potential of these substances in various clinical settings.

Articles (24)

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2025

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2020

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2020

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2020

Collaborators (20)

Kim Kuypers

Associate Professor

University of Maastricht

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Matthias E. Liechti

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Articles (24)

Case report: Well-tolerated MDMA-assisted therapy in a 32-year old female patient with advanced alcohol-induced liver cirrhosis

Pharmacokinetics, Pharmacodynamics, and Urinary Recovery of Oral Mescaline Hydrochloride in Healthy Participants

Acute effects of MDMA, MDA, lysine-MDMA, and lysine-MDA in a randomized, double-blind, placebo-controlled, crossover trial in healthy participants

Absolute Oral Bioavailability and Bioequivalence of LSD Base and Tartrate in a Double‐Blind, Placebo‐Controlled, Crossover Study

Pharmacokinetics and Pharmacodynamics of Intranasal Diacetylmorphine in Heroin-Assisted Treatment for Severe Opioid Use Disorder

Liquid chromatography–tandem mass spectrometry–based pharmacokinetic and metabolic analysis of 4-bromo-2,5-dimethoxyphenethylamine and its metabolites in human plasma

The effect of MDMA on anterior pituitary hormones: a secondary analysis of a randomized placebo-controlled trial

Neurophysin I: a reliable, novel, and robust biomarker for oxytocin

Implementing psychedelic-assisted therapy: History and characteristics of the Swiss limited medical use program

Clinical effects of cannabis compared to synthetic cannabinoid receptor agonists (SCRAs): a retrospective cohort study of presentations with acute toxicity to European hospitals between 2013 and 2020

Acute effects of R-MDMA, S-MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants

Derivatization-free determination of chiral plasma pharmacokinetics of MDMA and its enantiomers

Naturalistic psychedelic therapy: The role of relaxation and subjective drug effects in antidepressant response

In vitro and in vivo metabolism of psilocybin’s active metabolite psilocin

Development and validation of an LC-MS/MS method for quantifying diamorphine and its major metabolites 6-monoacetylmorphine, morphine, morphine-3-glucuronide, and morphine-6-glucuronide in human plasma

Inter-individual variability in neural response to low doses of LSD

Ketanserin exhibits dose- and concentration-proportional serotonin 2A receptor occupancy in healthy individuals: Relevance for psychedelic research

Knowledge gaps in psychedelic medicalisation: Clinical studies and regulatory aspects

Determinants of Admission to Critical Care Following Acute Recreational Drug Toxicity: A Euro-DEN Plus Study

Effective-connectivity of thalamocortical interactions following d-amphetamine, LSD, and MDMA administration

The Pharmacological Profile of Second Generation Pyrovalerone Cathinones and Related Cathinone Derivative

Comparative Untargeted Metabolomics Analysis of the Psychostimulants 3,4-Methylenedioxy-Methamphetamine (MDMA), Amphetamine, and the Novel Psychoactive Substance Mephedrone after Controlled Drug Administration to Humans

<i>Para</i>-Halogenation of Amphetamine and Methcathinone Increases the Mitochondrial Toxicity in Undifferentiated and Differentiated SH-SY5Y Cells

Hyperthermia Increases Neurotoxicity Associated with Novel Methcathinones

Collaborators (20)

Kim Kuypers

Alessandro Ceschi

Gesche Jürgens

Matteo Franchi

Tobias Zellner

Anne Eckert

Deborah Rudin

Marc Vogel

Knut Erik Hovda

Eef Theunissen

Patrick Fisher

Florian Eyer

Martina Boxler

Caroline Samer

Sergey Zakharov

Dino Luethi

Odd Martin Vallersnes

Gerhard Gründer

Evangelia Liakoni

Mihai Avram

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