Dino Luethi

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Research Associate & Lecturer

University Hospital Basel

Switzerland

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About

Dr. Dino Luethi is a Research Associate and Lecturer at the University Hospital Basel, Switzerland. His research focuses on pharmacokinetics and pharmacodynamics related to psychoactive substances, as evidenced by his recent articles on mescaline, MDMA, and LSD. Dr. Luethi's work also investigates the effects of various substances on serotonin transport and their implications for substance use disorder treatments.

Recent Grants

Grant: Close

Role of phosphatidylinositol 4,5-bisphosphate in substrate-induced serotonin transporter oligomer dissociation

Open Date: 2022-02-01

Close Date: 2023-01-31

Grant: Close

Serotonin transporter oligomerization as potential target of antidepressants and drugs of abuse

Open Date: 2020-07-01

Close Date: 2021-12-31

Grant: Close

Effects of synthetic cathinones on subunit stoichiometry and function of the dopamine transporter

Open Date: 2019-01-01

Close Date: 2020-06-30

Articles (20)

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2022

Collaborators (8)

Matthias E. Liechti

Professor

University of Basel

SWITZERLAND

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Ruth Birner-Gruenberger

TU Wien

AUSTRIA

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Anne Eckert

Professor of Experimental Psychiatry

University of Basel

SWITZERLAND

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Deborah Rudin

Postdoc, Head Profiling

University Hospital Basel

SWITZERLAND

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Isabella Burger

Universität Wien

AUSTRIA

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Jae-Won Yang

Medical University of Vienna

AUSTRIA

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Volodymyr Korkhov

ETH Zürich

SWITZERLAND

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Thomas Stockner

Assoc. Prof.

Medical University of Vienna

AUSTRIA

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Dino Luethi

Research Interests

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About

Recent Grants

Articles (20)

Pharmacokinetics, Pharmacodynamics, and Urinary Recovery of Oral Mescaline Hydrochloride in Healthy Participants

Acute effects of MDMA, MDA, lysine-MDMA, and lysine-MDA in a randomized, double-blind, placebo-controlled, crossover trial in healthy participants

Cell membrane cholesterol affects serotonin transporter efflux due to altered transporter oligomerization

Absolute Oral Bioavailability and Bioequivalence of LSD Base and Tartrate in a Double‐Blind, Placebo‐Controlled, Crossover Study

Pharmacokinetics and Pharmacodynamics of Intranasal Diacetylmorphine in Heroin-Assisted Treatment for Severe Opioid Use Disorder

Acute Effects and Pharmacokinetics of LSD after Paroxetine or Placebo Pre‐Administration in a Randomized, Double‐Blind, Cross‐Over Phase I Trial

Liquid chromatography–tandem mass spectrometry–based pharmacokinetic and metabolic analysis of 4-bromo-2,5-dimethoxyphenethylamine and its metabolites in human plasma

Acute effects of R-MDMA, S-MDMA, and racemic MDMA in a randomized double-blind cross-over trial in healthy participants

Derivatization-free determination of chiral plasma pharmacokinetics of MDMA and its enantiomers

Acute dose-dependent effects of mescaline in a double-blind placebo-controlled study in healthy subjects

Comparative acute effects of mescaline, lysergic acid diethylamide, and psilocybin in a randomized, double-blind, placebo-controlled cross-over study in healthy participants.

Acute effects of intravenous DMT in a randomized placebo-controlled study in healthy participants.

Editorial: Old and new psychoactive substances: Pharmacology and potential applications.

Phosphatidylinositol 4,5-bisphosphate (PIP2) facilitates norepinephrine transporter dimerization and modulates substrate efflux

Structural basis of organic cation transporter-3 inhibition

Use of the head-twitch response to investigate the structure-activity relationships of 4-thio-substituted 2,5-dimethoxyphenylalkylamines.

Liquid chromatography-tandem mass spectrometry method for the bioanalysis of N,N-dimethyltryptamine (DMT) and its metabolites DMT-N-oxide and indole-3-acetic acid in human plasma.

Pharmacological characterization of 3,4-methylenedioxyamphetamine (MDA) analogs and two amphetamine-based compounds: N,α-DEPEA and DPIA

Pharmacological characterization of 3,4-methylenedioxamphetamine (MDA) analogs and two amphetamine-based compounds: N,alpha-DEPEA and DPIA

Correction to: Designer drugs: mechanism of action and adverse effects

Collaborators (8)

Matthias E. Liechti

Ruth Birner-Gruenberger

Anne Eckert

Deborah Rudin

Isabella Burger

Jae-Won Yang

Volodymyr Korkhov

Thomas Stockner

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