Mauro DACASTO

Full Professor in Veterinary Pharmacology & Toxicology

University of Padua

Italy

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Mauro DACASTO is a Full Professor in Veterinary Pharmacology & Toxicology at the University of Padua, Italy. His research focuses on the genetic and molecular mechanisms underlying drug interactions, hepatotoxicity, and cancer in both canine and bovine models. Recent publications include studies on cytochrome P450 interactions, mutations in mast cell tumors, and transcriptomic analyses related to environmental toxins. His work contributes to enhancing the understanding of pharmacological effects and disease mechanisms in veterinary medicine.

Articles (17)

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2025

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2022

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2021

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2020

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2020

Collaborators (10)

Enrico NOVELLI

Professore ordinario

University of Padova

ITALY

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Roberto Piva

University of Turin

ITALY

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Luca Aresu

Full Professor

Università degli Studi di Torino

ITALY

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Mery GIANTIN

University of Padua

ITALY

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Damiano Stefanello

University of Milan

ITALY

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VALERIA GRIECO

Assosiate Prof

Università degli Studi di Torino

ITALY

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Andrea Barbarossa

Associate Professor

University of Bologna

ITALY

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Claudia Sissi

ITALY

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anna zaghini

University of Bologna

ITALY

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FLAVIA GIROLAMI

Associate Professor

Università degli Studi di Torino

ITALY

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Mauro DACASTO

Research Interests

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About

Articles (17)

A genetic algorithm-based approach for quantitative prediction of drug-drug interactions caused by cytochrome P450 3A inhibitors and inducers in dogs and cats

CYP1B1 Knockout in a Bovine Hepatocyte-like Cell Line (BFH12) Unveils Its Role in Liver Homeostasis and Aflatoxin B1-Induced Hepatotoxicity

Expression Profile of Twelve Transcripts as a Supporting Tool for the Molecular Characterization of Canine Cutaneous Mast Cell Tumors at Diagnosis: Association with Histological Grading and Clinical Staging

A Whole-Transcriptomic Analysis of Canine Oral Melanoma: A Chance to Disclose the Radiotherapy Effect and Outcome-Associated Gene Signature

Sub-acute exposure of male guppies (Poecilia reticulata) to environmentally relevant concentrations of PFOA and GenX induces significant changes in the testis transcriptome and reproductive traits

Mutational Landscape of KIT Proto-Oncogene Coding Sequence in 62 Canine Cutaneous and Subcutaneous Mast Cell Tumors

Impact of Missense Mutations on AFB1 Metabolism in Bovine Cytochrome P4503A Isoforms: A Computational Mutagenesis and Molecular Docking Analysis

Discovering the Protective Effects of Quercetin on Aflatoxin B1-Induced Toxicity in Bovine Foetal Hepatocyte-Derived Cells (BFH12)

An In Vivo Whole-Transcriptomic Approach to Assess Developmental and Reproductive Impairments Caused by Flumequine in Daphnia magna

Induction by Phenobarbital of Phase I and II Xenobiotic-Metabolizing Enzymes in Bovine Liver: An Overall Catalytic and Immunochemical Characterization

Deepening the Whole Transcriptomics of Bovine Liver Cells Exposed to AFB1: A Spotlight on Toll-like Receptor 2

Hypermethylation-Mediated Silencing of <i>CIDEA</i>, <i>MAL</i> and <i>PCDH17</i> Tumour Suppressor Genes in Canine DLBCL: From Multi-Omics Analyses to Mechanistic Studies

Does Bentonite Cause Cytotoxic and Whole-Transcriptomic Adverse Effects in Enterocytes When Used to Reduce Aflatoxin B1 Exposure?

Discovering the Protective Effects of Resveratrol on Aflatoxin B1-Induced Toxicity: A Whole Transcriptomic Study in a Bovine Hepatocyte Cell Line

G-Quadruplex Modulation of SP1 Functional Binding Sites at the KIT Proximal Promoter

Midazolam oxidation in cattle liver microsomes: The role of cytochrome P450 3A

Curcumin Mitigates AFB1-Induced Hepatic Toxicity by Triggering Cattle Antioxidant and Anti-inflammatory Pathways: A Whole Transcriptomic In Vitro Study

Collaborators (10)

Enrico NOVELLI

Roberto Piva

Luca Aresu

Mery GIANTIN

Damiano Stefanello

VALERIA GRIECO

Andrea Barbarossa

Claudia Sissi

anna zaghini

FLAVIA GIROLAMI

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