Mauro Maccarrone

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Professor and Chair of Biochemistry

University of L'Aquila

Italy

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About

Professor Mauro Maccarrone serves as the Chair of Biochemistry at Università degli Studi dell'Aquila, Italy. His research focuses on the interactions between bioactive lipids and neurodegeneration, as evidenced by his recent articles on endocannabinoids, sphingosine-1-phosphate, and the effects of phytocannabinoids on cellular processes. He is particularly interested in the role of lipid signaling in chronic diseases and neuroinflammation.

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Mechanistic insights into Alzheimer’s disease: Epigenetic and immunomodulatory remodelling of endocannabinoid signalling

Open Date: 2018-01-01

Close Date: 2020-12-01

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Collaborators (13)

MARINA FAVA

Università Campus Bio-Medico

ITALY

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Sapienza University of Rome

ITALY

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Jesmond Dalli

Professor in Molecular Pharmacology, Sir Henry Dale Fellow, Lipid Mediator Unit Director

William Harvey Research Institute

UNITED KINGDOM

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PAOLO TUCCI

Associate Professor

Università degli Studi di Foggia

ITALY

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Francesca Liberatore

Istituto Neurologico Mediterraneo

ITALY

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Mauro Maccarrone

Research Interests

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About

Recent Grants

Articles (22)

New insights into the crosstalk between endocannabinoids and sphingosine-1-phosphate

FAAH Modulators from Natural Sources: A Collection of New Potential Drugs

The Effect of Phytocannabinoids and Endocannabinoids on Nrf2 Activity in the Central Nervous System and Periphery

Interaction between α-Synuclein and Bioactive Lipids: Neurodegeneration, Disease Biomarkers and Emerging Therapies

The endocannabinoid anandamide activates pro‐resolving pathways in human primary macrophages by engaging both CB2 and GPR18 receptors

Cellular and Molecular Effects of Microgravity on the Immune System: A Focus on Bioactive Lipids

Conformational Dynamics of Lipoxygenases and Their Interaction with Biological Membranes

Simulated Microgravity Affects Pro-Resolving Properties of Primary Human Monocytes

Bioactive signalling lipids as drivers of chronic liver diseases

FAAH Inhibition Counteracts Neuroinflammation via Autophagy Recovery in AD Models

Effects of Long-Term Oral Administration of N-Palmitoylethanolamine in Subjects with Mild Cognitive Impairment: Study Protocol

Oxidative Stress in Postmenopausal Women with or without Obesity

Dysregulation of Resolvin E1 Metabolism and Signaling in a Light-Damage Model of Age-Related Macular Degeneration

Goods and Bads of the Endocannabinoid System as a Therapeutic Target: Lessons Learned after 30 Years

Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells

Endocannabinoid System Components of the Female Mouse Reproductive Tract Are Modulated during Reproductive Aging

Aβ Chronic Exposure Promotes an Activation State of Microglia through Endocannabinoid Signalling Imbalance

Deciphering Complex Interactions in Bioactive Lipid Signaling

Rare Phytocannabinoids Exert Anti-Inflammatory Effects on Human Keratinocytes via the Endocannabinoid System and MAPK Signaling Pathway

Computational and Experimental Drug Repurposing of FDA-Approved Compounds Targeting the Cannabinoid Receptor CB1

Advanced Omics Techniques for Understanding Cochlear Genome, Epigenome, and Transcriptome in Health and Disease

Targeting mGlu1 Receptors in the Treatment of Motor and Cognitive Dysfunctions in Mice Modeling Type 1 Spinocerebellar Ataxia

Collaborators (13)

MARINA FAVA

Nico Antenucci

Ugo Nocentini

Caterina Conte

Dagmar Meyer zu Heringdorf

Anna Maria Sardanelli

Alessandro Leuti

Sergio Oddi

Simone Carotti

Luciano Saso

Jesmond Dalli

PAOLO TUCCI

Francesca Liberatore

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