Jesmond Dalli

Professor in Molecular Pharmacology, Sir Henry Dale Fellow, Lipid Mediator Unit Director

William Harvey Research Institute

United Kingdom

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About

Professor Jesmond Dalli is a faculty member in Molecular Pharmacology at the William Harvey Research Institute in the UK. He serves as a Sir Henry Dale Fellow and directs the Lipid Mediator Unit. His research focuses on intracellular signaling mechanisms, the development of methodologies for lipid mediator identification, and the role of specialized pro-resolving mediators in inflammatory responses.

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2025

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Collaborators (21)

MARINA FAVA

Università Campus Bio-Medico

ITALY

Jesmond Dalli

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Articles (20)

Intracellular and nuclear CXCR4 signaling promotes terminal erythroblast differentiation and enucleation

Targeting Inflammatory Imbalance in Chronic Kidney Disease: Focus on Anti-Inflammatory and Resolution Mediators

The endocannabinoid anandamide activates pro‐resolving pathways in human primary macrophages by engaging both CB2 and GPR18 receptors

Resolvin D2 prevents vascular remodeling, hypercontractility and endothelial dysfunction in obese hypertensive mice through modulation of vascular and proinflammatory factors

An LGR6 frameshift variant abrogates receptor expression on select leukocyte subsets and is associated with viral infections

Resolvin T4 enhances macrophage cholesterol efflux to reduce vascular disease

Development and Validation of Methodologies for the Identification of Specialized Pro-Resolving Lipid Mediators and Classic Eicosanoids in Biological Matrices

Efferocyte‐Derived MCTRs Metabolically Prime Macrophages for Continual Efferocytosis via Rac1‐Mediated Activation of Glycolysis

Reply to: Failure to apply standard limit-of-detection or limit-of-quantitation criteria to specialized pro-resolving mediator analysis incorrectly characterizes their presence in biological samples

Author Correction: A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae (Nature Communications, (2015), 6, 1, (7403), 10.1038/ncomms8403)

Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer

Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit

Lipid mediator n‐3 docosapentaenoic acid‐derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G‐protein‐coupled receptor

Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis

Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease

Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2n‐3 DPA

Loss of 15-lipoxygenase disrupts Treg differentiation altering their pro-resolving functions

Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education

Changes in brown adipose tissue lipid mediator signatures with aging, obesity, and DHA supplementation in female mice

Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis

Collaborators (21)

MARINA FAVA

Raquel Rodrigues Díez

Neil Dufton

Maria J. Moreno-Aliaga

Mauro Perretti

Christoph Schneider

Patricia Munroe

Johan Duchene

Xiaogang Feng

Sergio Oddi

Stephen Malin

Andreas Margraf

Trinidad Montero-Melendez

Tobias Tekath

Gabriele Ruffolo

Magdalena Flak

Vladimir S. Shavva

Marie Spreckley

Stefania Marzocco

Mauro Maccarrone

Trond V. Hansen

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