Megan Hitchins
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United StatesResearch Interests
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About
Professor Megan Hitchins is a faculty member at the Cedars-Sinai Medical Center Samuel Oschin Comprehensive Cancer Institute in the United States. Her research primarily focuses on colorectal cancer, particularly the role of MLH1 methylation and its implications in mismatch repair deficiency. She has contributed to significant advancements in understanding ctDNA-guided immunotherapy and the genetics of pancreatic ductal adenocarcinoma. Her recent articles explore various aspects of epigenetics and cancer therapy, highlighting the importance of constitutional MLH1 epimutations in cancer predisposition.
Recent Grants
Grant: Close
Discovery and verification of methylated circulating tumor DNA markers for the detection of colorectal cancer in subjects under 50 years of age
Open Date: 2021-07-01
Close Date: 2026-06-30
Grant: Close
The mechanistic basis for constitutional MLH1 methylation (epimutation)
Open Date: 2019-09-18
Close Date: 2024-07-31
Grant: Close
The role and underlying mechanisms of constitutional epigenetic silencing in cancer predisposition
Open Date: 2011-01-01
Close Date: 2013-12-31
Grant: Close
Mechanisms of induction and progression of childhood asthma: investigations in a mouse model
Open Date: 2010-01-01
Close Date: 2013-12-31
Grant: Close
The role and inheritance of constitutional epimutations in early-onset colorectal cancer.
Open Date: 2009-01-01
Close Date: 2012-12-31
Articles (13)
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2025
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2024
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2024
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2024
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2023
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2023
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2023
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2023
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2023
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2023
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2023
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2022
Year:
2022
Collaborators (7)
Peter Kimani
Associate Professor in Medical Statistics
University of Warwick
Dennis Hazelett
Assistant Professor
Cedars-Sinai Medical Center
Paula Climent-Cantó
Institut Mondor de recherche biomédicale
Jose Luis Soto
Associate Professor
Universidad de Alicante
Ayman Bannaga
Queen Elizabeth Hospital Birmingham
GiWon Shin
Assistant Professor
Washington University in Saint Louis School of Medicine
Fátima Marín Nieto
Institut d'Investigacions Biomèdiques de Barcelona
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