Melanie Ott

Professor

University of California, San Francisco

United States

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About

Melanie Ott is a Professor at the University of California, San Francisco, specializing in virology and immunology. Her recent research focuses on HIV, emerging viruses, and the interactions between host factors and viral pathogens. Notable publications include work on HIV latency, coronavirus inhibitors, and mechanisms of T-cell immunity against hepatitis C virus.

Articles (11)

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2025

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2025

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2024

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2024

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2024

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2023

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2022

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2022

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2021

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2020

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2020

Collaborators (10)

Douglas Nixon

Professor of Immunology in Medicine

Weill Cornell Medicine

UNITED STATES

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Irene Chen

Gladstone Institutes

UNITED STATES

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Manon Eckhardt

Gladstone Institutes

UNITED STATES

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Michelle R. Arkin

University of California

UNITED STATES

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Ursula Schulze-Gahmen

Gladstone Institutes

UNITED STATES

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Lisa Oestereich

Bernhard-Nocht-Institut für Tropenmedizin

GERMANY

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Or Gozani

Stanford University

UNITED STATES

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Lishomwa Ndhlovu

Professor

Weill Cornell Medical College

UNITED STATES

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Jennifer Hayashi

Assistant Professor

Vassar College

UNITED STATES

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Allison Groseth

Laboratory Head

Friedrich-Loeffler-Institut

GERMANY

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Melanie Ott

Research Interests

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About

Articles (11)

HIV-induced T cell quiescence and the origins of viral latency

Structure-based discovery of highly bioavailable, covalent, broad-spectrum coronavirus-MPro inhibitors with potent in vivo efficacy

Intracellular lipid droplets are exploited by Junín virus: a nucleoprotein-dependent process

Silencing the transcriptionally active HIV reservoir to improve treatment outcomes

Understanding emerging and re-emerging viruses to facilitate pandemic preparedness

The lysine methyltransferase SMYD5 amplifies HIV-1 transcription and is post-transcriptionally upregulated by Tat and USP11

Structure-function analysis of enterovirus protease 2A in complex with its essential host factor SETD3

Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system

A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection

Turning up the heat on HIV-1

A combinatorial view of old and new RNA polymerase II modifications

Collaborators (10)

Douglas Nixon

Irene Chen

Manon Eckhardt

Michelle R. Arkin

Ursula Schulze-Gahmen

Lisa Oestereich

Or Gozani

Lishomwa Ndhlovu

Jennifer Hayashi

Allison Groseth

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