Michael Kassiou

University of Sydney

Australia

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Articles (19)

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2024

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2023

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2022

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2022

Collaborators (15)

Yazi Ke

Macquarie University

AUSTRALIA

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Peter Rutledge

Prof.

University of Sydney

AUSTRALIA

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Claire Troakes

King’s College London

UNITED KINGDOM

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Michael Patrick Gray

University of Sydney

AUSTRALIA

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Mark Connor

Macquarie University

AUSTRALIA

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Elijah Genetzakis

University of Sydney

AUSTRALIA

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Muneer Ahamed

University of Queensland

AUSTRALIA

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Margaret Sunde

Professor of Molecular Biomedicine

University of Sydney

AUSTRALIA

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Lars Ittner

Macquarie University

AUSTRALIA

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Prita Riana Asih

Macquarie University

AUSTRALIA

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Marc-David Ruepp

King’s College London

UNITED KINGDOM

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Ann H. Kwan

University of Sydney

AUSTRALIA

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Fiona Bright

Macquarie University

AUSTRALIA

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Diane Hanger

King’s College London

UNITED KINGDOM

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Cara Louise Croft

Senior Lecturer in Neuroscience

Queen Mary University of London

UNITED KINGDOM

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Michael Kassiou

Research Interests

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Articles (19)

An Investigation on Linker Modifications of Cyanoguanidine‐Based P2X7 Receptor Antagonists

Unlocking therapeutic potential: the role of adamantane in drug discovery

Perphenazine–Macrocycle Conjugates Rapidly Sequester the Aβ42 Monomer and Prevent Formation of Toxic Oligomers and Amyloid

Synthesis and Preclinical Evaluation of Fluorinated 5-Azaindoles as CB2 PET Radioligands

High-Throughput Measure of Mitochondrial Superoxide Levels as a Marker of Coronary Artery Disease to Accelerate Drug Translation in Patient-Derived Endothelial Cells Using Opera Phenix® Technology

P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes

Late-stage Functionalization for Improving Drug-like Molecular Properties

An update on late-stage functionalization in today’s drug discovery

Imaging Brain Injury in Former National Football League Players

Biomarker discovery and development for frontotemporal dementia and amyotrophic lateral sclerosis

Differential mitochondrial protein interaction profile between human translocator protein and its A147T polymorphism variant

Development and clinical translation of P2X7 receptor antagonists: A potential therapeutic target in coronary artery disease?

Erratum: Evaluation of 18F-IAM6067 as a sigma-1 receptor PET tracer for neurodegeneration in vivo in rodents and in human tissue (Theranostics (2020) 10:18 (7938-7955) DOI: 10.7150/thno.47585)

Novel plasma protein binding analysis method for a PET tracer and its radiometabolites: A case study with [<sup>11</sup>C]SMW139 to explain the high uptake of radiometabolites in mouse brain

Pharmacological characterization of a structural hybrid P2X7R antagonist using ATP and LL-37

Purinergic P2X<sub>7</sub>Receptor: A Therapeutic Target in Amyotrophic Lateral Sclerosis

Quantification of the purinergic P2X<sub>7</sub> receptor with [<sup>11</sup>C]SMW139 improves through correction for brain-penetrating radiometabolites

Strategies for targeting the P2Y<sub>12</sub> receptor in the central nervous system

Tracer development for PET imaging of proteinopathies

Collaborators (15)

Yazi Ke

Peter Rutledge

Claire Troakes

Michael Patrick Gray

Mark Connor

Elijah Genetzakis

Muneer Ahamed

Margaret Sunde

Lars Ittner

Prita Riana Asih

Marc-David Ruepp

Ann H. Kwan

Fiona Bright

Diane Hanger

Cara Louise Croft

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