Michael Shen

Columbia University Irving Medical Center

United States

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Articles (15)

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2025

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2024

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2020

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2020

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2020

Collaborators (11)

Alessandro Vasciaveo

Assistant Professor

Sanford Burnham Prebys Medical Discovery Institute

UNITED STATES

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Edward Gelmann

Professor

University of Arizona

UNITED STATES

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Dean Tang

Professor & Chairperson

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Rahul Kumar

Research Assistant Professor of Oncology

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Daniel W. Youngstrom

University of Connecticut Health Center

UNITED STATES

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Gabor Balazsi

Henry Laufer Professor

Stony Brook University

UNITED STATES

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Emily Germain-Lee

Professor, Division Chief of Pediatric Endocrinology

University of Connecticut School of Medicine

UNITED STATES

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Andrea Alimonti

ETH Zürich

SWITZERLAND

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Maho Shibata

Assistant Professor

George Washington University

UNITED STATES

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Vesa Kaartinen

Professor

University of Michigan

UNITED STATES

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Eugene Douglass

Assistant Professor

University of Georgia

UNITED STATES

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Michael Shen

Research Interests

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Articles (15)

The regulatory architecture of the primed pluripotent cell state

Meta-analyses of mouse and human prostate single-cell transcriptomes reveal widespread epithelial plasticity in tissue regression, regeneration, and cancer.

Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells.

Rarγ-Foxa1 signaling promotes luminal identity in prostate progenitors and is disrupted in prostate cancer.

RNASEH2B loss and PARP inhibition in advanced prostate cancer

The Wnt-dependent master regulator NKX1-2 controls mouse pre-implantation development

Inactive PARP1 causes embryonic lethality and genome instability in a dominant-negative manner

Immune mechanisms shape the clonal landscape during early progression of prostate cancer.

OncoLoop: A network-based precision cancer medicine framework

B7-H3 as a Therapeutic Target in Advanced Prostate Cancer

Prostate cancer cell heterogeneity and plasticity: Insights from studies of genetically-engineered mouse models

Heterogeneity and complexity of the prostate epithelium: New findings from single-cell RNA sequencing studies

Functional redundancy of type I and type II receptors in the regulation of skeletal muscle growth by myostatin and activin A

CRISPR/Cas9-Mediated Point Mutation in Nkx3.1 Prolongs Protein Half-Life and Reverses Effects Nkx3.1 Allelic Loss

A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors.

Collaborators (11)

Alessandro Vasciaveo

Edward Gelmann

Dean Tang

Rahul Kumar

Daniel W. Youngstrom

Gabor Balazsi

Emily Germain-Lee

Andrea Alimonti

Maho Shibata

Vesa Kaartinen

Eugene Douglass

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