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Michael Sigal

Professor for Translational Gastrointestinal Oncology

Charité - Universitätsmedizin Berlin

Germany

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Research Interests

Cell Biology

30%

Microbiology

30%

Mucosal Biology

30%

Gastric Cancer

30%

Stem Cell Biology

20%

Wnt Signaling

20%

Gut Microbiota

20%

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Articles10

Association of Helicobacter Pylori Positivity with Risk of Disease and Mortality.

Article Link

Year:

2023

Biliary microbial patterns in primary sclerosing cholangitis are linked to poorer transplant-free survival.

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Year:

2023

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.

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Year:

2023

Hepatobiliary long-term consequences of COVID-19: dramatically increased rate of secondary sclerosing cholangitis in critically ill COVID-19 patients.

Article Link

Year:

2023

Osteopontin is a prognostic circulating biomarker in patients with neuroendocrine neoplasms.

Article Link

Year:

2023

Short-term mucosal disruption enables colibactin-producing E. coli to cause long-term perturbation of colonic homeostasis.

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Year:

2023

Unwelcome guests - the role of gland-associated Helicobacter pylori infection in gastric carcinogenesis.

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Year:

2023

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells

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Year:

2022

R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori–associated metaplasia in mice

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Year:

2022

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3‐Lgr4 axis

Article Link

Year:

2022

Collaborators8

Julian Heuberger

Charité - Universitätsmedizin Berlin

GERMANY

Andreas Edel

ChariteCentrum 7 fur Anasthesiologie OP-Management und Intensivmedizin

GERMANY

Lichao liu

Charité - Universitätsmedizin Berlin

GERMANY

Raphael Mohr

Charité - Universitätsmedizin Berlin

GERMANY

Kimberly Hartl

Charité - Universitätsmedizin Berlin

GERMANY

Klaus Rajewsky

Senior Group Leader and Professor

Max Delbrück Centrum für Molekulare Medizin Berlin Buch

GERMANY

Felix Balzer

Charité - Universitätsmedizin Berlin

GERMANY

Kai Markus Schneider

Assistant Professor, Research group leader

RWTH Aachen University

GERMANY

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