Julian Heuberger

Charité - Universitätsmedizin Berlin

Germany

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Articles (11)

Year:

2025

Year:

2023

Year:

2023

Year:

2022

Year:

2022

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2022

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2022

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2021

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2021

Year:

2021

Year:

2020

Collaborators (11)

Michael Sigal

Professor for Translational Gastrointestinal Oncology

Charité - Universitätsmedizin Berlin

GERMANY

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Qinyu Zhang

Lund University

SWEDEN

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Lichao liu

Charité - Universitätsmedizin Berlin

GERMANY

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Andrea Kranz

Technische Universität Dresden

GERMANY

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Xiangsheng Zuo

Assistant professor

The University of Texas MD Anderson Cancer Center

UNITED STATES

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Imad Shureiqi

Professor

University of Michigan

UNITED STATES

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Hugo de Jonge

University lecturer

University of Pavia

ITALY

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Kimberly Hartl

Charité - Universitätsmedizin Berlin

GERMANY

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Klaus Rajewsky

Senior Group Leader and Professor

Max Delbrück Centrum für Molekulare Medizin Berlin Buch

GERMANY

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Claudia Waskow

Professor

friedrich schiller universität

GERMANY

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Alexander Arnold

Charité - Universitätsmedizin Berlin

GERMANY

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Julian Heuberger

Research Interests

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Articles (11)

Extrusion of BMP2+ surface colonocytes promotes stromal remodeling and tissue regeneration

Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche.

Modulation of intestinal IL-37 expression and its impact on the epithelial innate immune response and barrier integrity.

Epigenetic modifier balances Mapk and Wnt signalling in differentiation of goblet and Paneth cells

Gastric stem cells promote inflammation and gland remodeling in response to Helicobacter pylori via Rspo3‐Lgr4 axis

BMP feed-forward loop promotes terminal differentiation in gastric glands and is interrupted by H. pylori-driven inflammation

R-spondin/YAP axis promotes gastric oxyntic gland regeneration and Helicobacter pylori-associated metaplasia in mice.

NF-κB determines Paneth versus goblet cell fate decision in the small intestine

High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53

MLL1 is required for maintenance of intestinal stem cells.

The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness

Collaborators (11)

Michael Sigal

Qinyu Zhang

Lichao liu

Andrea Kranz

Xiangsheng Zuo

Imad Shureiqi

Hugo de Jonge

Kimberly Hartl

Klaus Rajewsky

Claudia Waskow

Alexander Arnold

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