Michel Kranendonk

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Universidade de Aveiro

Portugal

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Recent Grants

Grant: Open

Discovering chronic inflammation biomarkers that define key stages in the Healthy-to-NASH (non- alcoholic steatohepatitis) transition to inform early prevention and treatment strategies

Open Date: 2022-12-01

Close Date: 2026-11-01

Grant: Close

Domain Dynamics and Control of ELectron flux

Open Date: 2014-05-01

Close Date: 2018-04-01

Grant: Close

Domain Dynamics and Control of ELectron flux

Open Date: 2014-05-01

Close Date: 2018-04-01

Grant: Close

Molecular and Cellular Effects of Human Mutations in Cytochrome P450 Reductase

Open Date: 2013-04-01

Close Date: 2017-02-28

Grant: Close

Bioactivation routes of the anti-HIV drug Nevirapine: identification of reactive metabolites and mutagenic potential

Open Date: 2011-02-01

Close Date: 2014-02-28

Articles (13)

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2024

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2024

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2024

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2023

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2022

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2022

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2022

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2021

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2021

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2021

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2021

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2021

Year:

2020

Collaborators (7)

Cristina M. M. Almeida

Faculty of Pharmacy, University of Lisbon

PORTUGAL

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Gabriela Almeida

Associate Professor

Egas Moniz Cooperativa de Ensino Superior CRL

PORTUGAL

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Leonard Nelson

Professor of Human Liver Biological Engineering

Edinburgh Napier University

UNITED KINGDOM

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Patricia Raquel dos Santos Rodrigues

Cardiff University

UNITED KINGDOM

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Francisco Esteves

Professor Adjunto Convidado

Instituto Politécnico de Leiria

PORTUGAL

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Maria Joao Silva

Investigator / Head of R&I Group on Genetic Toxicology

National Institute of Health Dr. Ricardo Jorge

PORTUGAL

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Antonio Sebastião Rodrigues

Associate Professor Genetics with Aggregation

Faculty of Medicine, University of Lisbon

PORTUGAL

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Michel Kranendonk

Research Interests

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Recent Grants

Articles (13)

Pleiotropy of Progesterone Receptor Membrane Component 1 in Modulation of Cytochrome P450 Activity

Challenges of the Application of In Vitro Digestion for Nanomaterials Safety Assessment

Roadmap to DILI research in Europe. A proposal from COST action ProEuroDILINet

Single Mutations in Cytochrome P450 Oxidoreductase Can Alter the Specificity of Human Cytochrome P450 1A2-Mediated Caffeine Metabolism

The Complex Dynamic of Phase I Drug Metabolism in the Early Stages of Doxorubicin Resistance in Breast Cancer Cells

Toxicological Assessment of Cellulose Nanomaterials: Oral Exposure

Motor dysfunction in Drosophila melanogaster as a biomarker for developmental neurotoxicity.

Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O2 Control and the Natural Electron Donor

Front Cover: Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O2 Control and the Natural Electron Donor (ChemElectroChem 3/2021)

Electrochemical Activity of Cytochrome P450 1A2: The Relevance of O2 Control and the Natural Electron Donor

The Central Role of Cytochrome P450 in Xenobiotic Metabolism—A Brief Review on a Fascinating Enzyme Family

Advanced preclinical models for evaluation of drug-induced liver injury – consensus statement by the European Drug-Induced Liver Injury Network [PRO-EURO-DILI-NET]

Interaction Modes of Microsomal Cytochrome P450s with Its Reductase and the Role of Substrate Binding

Collaborators (7)

Cristina M. M. Almeida

Gabriela Almeida

Leonard Nelson

Patricia Raquel dos Santos Rodrigues

Francisco Esteves

Maria Joao Silva

Antonio Sebastião Rodrigues

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