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Michelle Linterman

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Chief Scientist & Programme Leader

Malaghan Institute of Medical Research

New Zealand

Research Interests

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Recent Grants

Grant: Open

(Lost-Tfh) Lost in space: How spatial dysregulation of T follicular helper cells impairs vaccine responses in ageing

Open Date: 2022-06-30

Close Date: 2027-06-29

Grant: Close

Impaired selection of germinal centre B cells in ageing diminishes the quality of antibody mediated immunity upon vaccination

Open Date: 2021-09-30

Close Date: 2024-09-29

Grant: Close

SARS COV2 vaccine ResPonse In Obesity - SCORPIO study

Open Date: 2021-08-11

Close Date: 2023-03-30

Grant: Close

Boosting vaccine responses in older persons

Open Date: 2020-06-01

Close Date: 2022-01-02

Grant: Close

16ALERT: BD FACS-Aria Fusion - strengthening the cell sorting capabilities of Babraham Institute Flow Core to enrich world-class science

Open Date: 2017-08-14

Close Date: 2018-08-13

Articles (20)

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Collaborators (23)

Susanna Dunachie

Professor at University of Oxford

University of Oxford

UNITED KINGDOM

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Nicholas Matheson

Associate Professor of Virology

University of Cambridge

UNITED KINGDOM

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I. Sadaf Farooqi

Professor of Metabolism and Medicine

University of Cambridge

UNITED KINGDOM

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Edward Carr

Seconded clinician scientist group leader

The Francis Crick Institute

UNITED KINGDOM

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Adrian Liston

UNITED KINGDOM

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Martin Potts

UNITED KINGDOM

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Matteo Iannacone

Director

Vita-Salute San Raffaele University

ITALY

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Agatha van der Klaauw

Clinical lecturer in Metabolic Medicine

University of Cambridge

UNITED KINGDOM

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Michel Cogné

University professor

Université de Rennes 1

FRANCE

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Oliver Burton

Senior Scientist

University of Cambridge

UNITED KINGDOM

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Lise Estcourt

University of Oxford

UNITED KINGDOM

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Michael Meyer-Hermann

Head of Department

Helmholtz Centre for Infection Research

GERMANY

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FREDERIC FIORE

Head of Genetic Engineering Department, PhD

INSERM Délégation régionale Provence Alpes Cote d'Azur et Corse

FRANCE

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Jonathan Houseley

Group leader and Head of Knowledge Exchange and Commercialisation

Babraham Institute

UNITED KINGDOM

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Nathalie Kingston

Research Professor

University of Cambridge

UNITED KINGDOM

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Hamish W King

Laboratory Head

Walter and Eliza Hall Institute of Medical Research

AUSTRALIA

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Dirk Baumjohann

Associate Professor

University of Bonn

GERMANY

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Louise Webb

Principal Staff Scientist

Babraham Institute

UNITED KINGDOM

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Louise Matheson

Senior Staff Scientist

Babraham Institute

UNITED KINGDOM

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Emma Slack

Professor at ETH Zürich

ETH Zürich

SWITZERLAND

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James Thaventhiran

MRC Toxicology Unit

UNITED KINGDOM

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James Dooley

Research Professor

University of Cambridge

UNITED KINGDOM

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Edith Marcial-Juárez

University of Birmingham

UNITED KINGDOM

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ApplyKite TwinLearns as you apply

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Michelle Linterman

Research Interests

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Recent Grants

Articles (20)

Gene delivery of immunomodulatory cytokines to the lung preserves respiratory function during inflammatory challenge

Mucosal tissue cues shape B cell memory through the IgA BCR

Spatial Profiling of Germinal Centers in Mouse Secondary Lymphoid Organs Using MACSima Imaging Cyclic Staining Technology

Targeting T follicular helper cells for lifelong health

Highlights of 2025: advances in germinal centers

IL‐2 silencing enables Tfh cell expansion during vaccination but is redundant for antibody production

Transient disruption of T cell help impairs germinal center dynamics and memory responses

Rethinking Immunity in Tissues: The Biology of Tertiary Lymphoid Structures

Germinal center formation is resilient to CD69 deletion on T follicular helper cells

RNA-binding proteins control the G2–M checkpoint of the germinal center B cell

Tertiary Lymphoid Structures Across Organs: Context, Composition, and Clinical Levers

The cellular factors that impair the germinal center in advanced age

Lung B cells in ectopic germinal centers undergo affinity maturation

ZFP318 fuels memory B cells for success

Highlight of 2023: Advances in germinal centers

Accelerated waning of the humoral response to COVID-19 vaccines in obesity

Spatial dysregulation of T follicular helper cells impairs vaccine responses in aging.

Atypical B cells and impaired SARS-CoV-2 neutralization following heterologous vaccination in the elderly.

B Cells from Aged Mice Do Not Have Intrinsic Defects in Affinity Maturation in Response to Immunization

Age-dependent changes in T follicular helper cells shape the humoral immune response to vaccination.

Collaborators (23)

Susanna Dunachie

Nicholas Matheson

I. Sadaf Farooqi

Edward Carr

Adrian Liston

Martin Potts

Matteo Iannacone

Agatha van der Klaauw

Michel Cogné

Oliver Burton

Lise Estcourt

Michael Meyer-Hermann

FREDERIC FIORE

Jonathan Houseley

Nathalie Kingston

Hamish W King

Dirk Baumjohann

Louise Webb

Louise Matheson

Emma Slack

James Thaventhiran

James Dooley

Edith Marcial-Juárez

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