Miguel Alcalde

CSIC Research Professor

Spain

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Dr. Miguel Alcalde is a CSIC Research Professor at the Institute of Catalysis and Petrochemistry (ICP) in Spain. His research focuses on enzyme engineering, particularly in the development and application of peroxygenases for various oxidative transformations. Recent publications highlight his work on recombinant enzymes, structural characterization, and directed evolution strategies for enhancing enzyme activity and selectivity.

Articles (15)

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2025

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2025

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2025

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2024

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2024

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2023

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2022

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2022

Collaborators (8)

Selin Kara

Head of the Institute / Prof. Dr.-Ing. habil.

Leibniz University Hannover

GERMANY

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Lars-Erik Meyer

Lecturer and researcher

Leibniz University Hannover

GERMANY

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John Woodley

Professor at Technical University of Denmark

Technical University of Denmark

DENMARK

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Frank Hollmann

Professor

Delft University of Technology

NETHERLANDS

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Juliet Victoria

Technical University of Denmark

DENMARK

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Ewald Jongkind

Delft University of Technology

NETHERLANDS

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Caroline Paul

Assistant Professor

Delft University of Technology

NETHERLANDS

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Katarzyna Świderek

Profesor Titular de Universidad / Associate professor

Universitat Jaume I

SPAIN

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Miguel Alcalde

Research Interests

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About

Articles (15)

Engineering the Tobacco Etch Virus Protease toward a Platform for Traceless Cleavage Using Distal Site Prediction and Smart Library Design

Characterization of Recombinant Unspecific Peroxygenase from Candolleomyces aberdarensis Through Crystallographic and Substrate Selectivity Studies

Stable and Promiscuous Galactose Oxidases Engineered by Directed Evolution, Atomistic Design, and Ancestral Sequence Reconstruction

Enzyme Benchmarking with Polyethylene Furanoate Soluble Scaffolds for Directed Evolution of PEFases

Structural Insights and Reaction Profile of a New Unspecific Peroxygenase from Marasmius wettsteinii Produced in a Tandem-Yeast Expression System

Toward Kilogram-Scale Peroxygenase-Catalyzed Oxyfunctionalization of Cyclohexane

A 3D printable synthetic hydrogel as an immobilization matrix for continuous synthesis with fungal peroxygenases

Conversion of Unsaturated Short- to Medium-Chain Fatty Acids by Unspecific Peroxygenases (UPOs)

Peroxygenase‐Catalysed Selective Oxidation of Silanes to Silanols

Peroxygenase‐Catalysed Selective Oxidation of Silanes to Silanols

Peroxygenase‐Promoted Enzymatic Cascades for the Valorisation of Fatty Acids

Unspecific peroxygenases: The pot of gold at the end of the oxyfunctionalization rainbow?

Repertoire of Computationally Designed Peroxygenases for Enantiodivergent C–H Oxyfunctionalization Reactions

Designed High-Redox Potential Laccases Exhibit High Functional Diversity

Efficient Base-Catalyzed Kemp Elimination in an Engineered Ancestral Enzyme

Collaborators (8)

Selin Kara

Lars-Erik Meyer

John Woodley

Frank Hollmann

Juliet Victoria

Ewald Jongkind

Caroline Paul

Katarzyna Świderek

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