Miikka Vikkula

Full Professor of Human Genetics

Université catholique de Louvain

Belgium

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About

Miikka Vikkula is a Full Professor of Human Genetics at Université catholique de Louvain in Belgium. His research primarily focuses on cerebrovascular anomalies, vascular malformations, and orofacial clefts, as evidenced by his recent publications. His work employs various models, including zebrafish, to explore the underlying genetic and molecular mechanisms contributing to these conditions.

Articles (19)

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2025

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2021

Collaborators (6)

Taija Makinen

Professor

Uppsala University

SWEDEN

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Isabelle Quere

Professor

University of Montpellier

FRANCE

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Pascal Brouillard

UCLouvain

BELGIUM

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Kari Alitalo

University of Helsinki

FINLAND

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Ondine Cleaver

Associate Professor

University of Texas Southwestern Medical Center

UNITED STATES

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Jorge Andrade

Berlin Institute of Health at Charité - Universitätsmedizin Berlin

GERMANY

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Miikka Vikkula

Research Interests

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About

Articles (19)

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations

Reversal of cerebrovascular anomalies in a zebrafish model of vein of Galen aneurysm

Whole exome sequencing in 18 Brazilian families with vertical transmission of non-syndromic oral clefts

Extracranial arteriovenous malformations: towards etiology-based therapeutic management

Four putative pathogenic ARHGAP29 variants in patients with non-syndromic orofacial clefts (NsOFC)

Targeted treatments for vascular malformations: current state of the art

Molecular investigation in individuals with orofacial clefts and microphthalmia-anophthalmia-coloboma spectrum

Targeted treatment in complex lymphatic anomaly: a case of synergistic efficacy of trametinib and sirolimus

BiallelicANGPT2loss-of-function causes severe early-onset non-immune hydrops fetalis

Excalibur: A new ensemble method based on an optimal combination of aggregation tests for rare-variant association testing for sequencing data

SATB2-Associated Syndrome Due to a c.715C>T:p(Arg239*) Variant in Adulthood: Natural History and Literature Review

Rare variant association on unrelated individuals in case–control studies using aggregation tests: existing methods and current limitations

Recalibrating vascular malformations and mechanotransduction by pharmacological intervention

Molecular pathways and possible therapies for head and neck vascular anomalies

Case report study of thalidomide therapy in 18 patients with severe arteriovenous malformations

Primary lymphoedema

Hypotrichosis‐lymphedema‐telangiectasia syndrome: Report of ileal atresia associated with a SOX18 de novo pathogenic variant and review of the phenotypic spectrum

Genetic Basis and Therapies for Vascular Anomalies

Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies

Collaborators (6)

Taija Makinen

Isabelle Quere

Pascal Brouillard

Kari Alitalo

Ondine Cleaver

Jorge Andrade

Make your next move.

Miikka Vikkula

Research Interests

Explore related searches

Contact this professor

About

Articles (19)

Angiopoietin–TIE2 feedforward circuit promotes PIK3CA-driven venous malformations

Reversal of cerebrovascular anomalies in a zebrafish model of vein of Galen aneurysm

Whole exome sequencing in 18 Brazilian families with vertical transmission of non-syndromic oral clefts

Extracranial arteriovenous malformations: towards etiology-based therapeutic management

Four putative pathogenic ARHGAP29 variants in patients with non-syndromic orofacial clefts (NsOFC)

Targeted treatments for vascular malformations: current state of the art

Molecular investigation in individuals with orofacial clefts and microphthalmia-anophthalmia-coloboma spectrum

Targeted treatment in complex lymphatic anomaly: a case of synergistic efficacy of trametinib and sirolimus

BiallelicANGPT2loss-of-function causes severe early-onset non-immune hydrops fetalis

Excalibur: A new ensemble method based on an optimal combination of aggregation tests for rare-variant association testing for sequencing data

SATB2-Associated Syndrome Due to a c.715C>T:p(Arg239*) Variant in Adulthood: Natural History and Literature Review

Rare variant association on unrelated individuals in case–control studies using aggregation tests: existing methods and current limitations

Recalibrating vascular malformations and mechanotransduction by pharmacological intervention

Molecular pathways and possible therapies for head and neck vascular anomalies

Case report study of thalidomide therapy in 18 patients with severe arteriovenous malformation﻿s

Primary lymphoedema

Hypotrichosis‐lymphedema‐telangiectasia syndrome: Report of ileal atresia associated with a SOX18 de novo pathogenic variant and review of the phenotypic spectrum

Genetic Basis and Therapies for Vascular Anomalies

Lymphatic Malformations: Genetics, Mechanisms and Therapeutic Strategies

Collaborators (6)

Taija Makinen

Isabelle Quere

Pascal Brouillard

Kari Alitalo

Ondine Cleaver

Jorge Andrade

Make your next move.

Case report study of thalidomide therapy in 18 patients with severe arteriovenous malformations