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Mikko Taipale

Professor

University of Toronto

Canada

Research Interests

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About

Dr. Mikko Taipale is an Associate Professor at the University of Toronto, Canada. His research focuses on molecular biology, specifically in the areas of intracellular delivery systems, transcriptional regulation, and CRISPR technologies. Recent publications include studies on the functional characterization of transcriptional activators and the mechanisms regulating mTORC1 activation. His work contributes to the understanding of cellular processes and therapeutic developments in the field.

Articles (15)

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2026

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2025

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2025

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2025

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2024

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2022

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2022

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2022

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2021

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2021

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2020

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2020

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2020

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2020

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2020

Collaborators (9)

Finlay Maguire

Associate Professor

Dalhousie University

CANADA

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Shahid Mukhtar

Professor

Clemson University

UNITED STATES

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Dae-Kyum Kim

Associate Member

Roswell Park Comprehensive Cancer Center

UNITED STATES

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Robert A. Batey

Associate

University of Toronto

CANADA

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Stephen Orlicky

Lunenfeld-Tanenbaum Research Institute

CANADA

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Dirk Fasshauer

Associate Professor

University of Lausanne

SWITZERLAND

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REBECCA VOORHEES

Assistant Professor

California Institute of Technology

UNITED STATES

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Geoffrey Hesketh

Assistant Professor

Dalhousie University

CANADA

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Guy Caldwell

University Distinguished Research Professor

The University of Alabama

UNITED STATES

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Mikko Taipale

Research Interests

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About

Articles (15)

Systematic discovery of pathogen effector functions across human pathogens and pathways

Pathogenesis and transmission of SARS-CoV-2 D614G, Alpha, Gamma, Delta, and Omicron variants in golden hamsters

What is the current bottleneck in mapping molecular interaction networks?

Comprehensively Testing the Function of Missense Variation in the STK11 Tumour Suppressor

An enhanced intracellular delivery platform based on a distant diphtheria toxin homolog that evades pre-existing antitoxin antibodies

HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state

Identification and functional characterization of transcriptional activators in human cells

Voices on technology: The molecular biologists’ ever-expanding toy box

A conformational switch driven by phosphorylation regulates the activity of the evolutionarily conserved SNARE Ykt6

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains

An efficient KRAB domain for CRISPRi applications in human cells

The GATOR–Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acids

Functional characterization of a PROTAC directed against BRAF mutant V600E

A Comprehensive, Flexible Collection of SARS-CoV-2 Coding Regions

Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins

Collaborators (9)

Finlay Maguire

Shahid Mukhtar

Dae-Kyum Kim

Robert A. Batey

Stephen Orlicky

Dirk Fasshauer

REBECCA VOORHEES

Geoffrey Hesketh

Guy Caldwell

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