Miranda Nabben

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Assistant Professor

Maastricht University Medical Centre

Netherlands

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About

Miranda Nabben is an Assistant Professor at Maastricht University Medical Centre in the Netherlands. Her research primarily focuses on cardiac metabolism, specifically the clinical and metabolic consequences of genetic variants in dilated cardiomyopathy, as well as the impact of traditional Chinese medicine on cardiac function. She has published several articles exploring topics ranging from the NRF2/β3-Adrenoreceptor axis in cardiac stress to the effects of ketone body exposure on insulin sensitivity in cardiomyocytes.

Recent Grants

Grant: Close

Are men bigger sweet-hearts? Molecular metabolic differences at the basis of gender-specific cardiac pressure overload disorders

Open Date: 2020-01-01

Close Date: 2024-01-01

Grant: Close

Amino acids as an unconventional therapy to treat the diabetic heart

Open Date: 2020-01-01

Close Date: 2022-01-01

Grant: Close

Defining targets to protect the non-diabetic and diabetic heart from transition to failure; a longitudinal in vivo approach

Open Date: 2013-01-01

Close Date: 2017-01-01

Grant: Close

The role of UCP3 in cardiac hypertrophy and heart failure

Open Date: 2010-01-01

Close Date: 2011-01-01

Articles (17)

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2025

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2023

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2022

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2022

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2022

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2022

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2022

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2021

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2021

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2021

Collaborators (10)

Sophie Stroeks

University of Maastricht

NETHERLANDS

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Elizabeth A.V. Jones

University of Maastricht

NETHERLANDS

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Ganesh Halade

Associate Professor

University of South Florida

UNITED STATES

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Ida Gjervold Lunde

Head of Center and Professor

Oslo University Hospital

NORWAY

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Diederik Kuster

Assistant Professor

VU medisch centrum

NETHERLANDS

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Joseph Dewulf

Head of Laboratory of Bochemical Genetics and newborn screening

Cliniques Universitaires Saint-Luc

BELGIUM

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Michiel Henkens

Maastricht University Medical Centre

NETHERLANDS

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Anne Hafstad

Professor

UiT The Arctic University of Norway

NORWAY

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B Daan Westenbrink

NETHERLANDS

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Michinari Nakamura

Rutgers New Jersey Medical School

UNITED STATES

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Miranda Nabben

Research Interests

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About

Recent Grants

Articles (17)

An NRF2/β3-Adrenoreceptor Axis Drives a Sustained Antioxidant and Metabolic Rewiring Through the Pentose-Phosphate Pathway to Alleviate Cardiac Stress

Clinical and metabolic consequences of a historic pathogenic lamin A/C founder variant

Specific Compounds Derived from Traditional Chinese Medicine Ameliorate Lipid-Induced Contractile Dysfunction in Cardiomyocytes

Glycolysis-Mediated Activation of v-ATPase by Nicotinamide Mononucleotide Ameliorates Lipid-Induced Cardiomyopathy by Repressing the CD36-TLR4 Axis

J147 Affects Cognition And Anxiety After Surgery In Zucker Rats

Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy

Clustering of Cardiac Transcriptome Profiles Reveals Unique Subgroups of Dilated Cardiomyopathy Patients

Guidelines on models of diabetic heart disease.

Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling

Ketone Body Exposure of Cardiomyocytes Impairs Insulin Sensitivity and Contractile Function through Vacuolar-Type H<sup>+</sup>-ATPase Disassembly—Rescue by Specific Amino Acid Supplementation

Endosomal v-ATPase as a Sensor Determining Myocardial Substrate Preference.

Evaluation of the Interaction of Sex Hormones and Cardiovascular Function and Health.

CD36 (SR-B2) as master regulator of cellular fatty acid homeostasis.

CD36 (SR-B2) as master regulator of cellular fatty acid homeostasis

Specific amino acid supplementation rescues the heart from lipid overload-induced insulin resistance and contractile dysfunction by targeting the endosomal mTOR-v-ATPase axis.

CD36 as a target for metabolic modulation therapy in cardiac disease.

Multiview deconvolution approximation multiphoton microscopy of tissues and zebrafish larvae.

Collaborators (10)

Sophie Stroeks

Elizabeth A.V. Jones

Ganesh Halade

Ida Gjervold Lunde

Diederik Kuster

Joseph Dewulf

Michiel Henkens

Anne Hafstad

B Daan Westenbrink

Michinari Nakamura

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