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Nathalie Chami

Assistant Professor | Group leader | AI & Human Health

Icahn School of Medicine at Mount Sinai

United States

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About

Dr. Nathalie Chami is an Assistant Professor at the Icahn School of Medicine at Mount Sinai, USA. Her research focuses on genetic factors related to body mass index, type 2 diabetes, and complex traits through whole genome sequencing analysis. Recent articles include studies on genetic risk alleles, chromosomal alterations, and the role of genetic variants in diverse populations.

Positions (1)

Nathalie Chami

University Name

Icahn School of Medicine at Mount Sinai

1 month ago

Postdoctoral Fellow and Bioinformatician Positions in Human Genetics, Genomics, and Precision Medicine

Nathalie Chami, Assistant Professor and Group Leader in the Windreich Department of AI & Human Health at the Icahn School of Medicine at Mount Sinai, is recruiting for multiple research positions in New York. The lab works on the human genetics and genomics of complex traits and rare disorders, with a strong emphasis on cardiometabolic traits and cardiovascular disease. Research methods include genome-wide genotyping, whole-exome sequencing, whole-genome sequencing, and integration with electronic health records, imaging data, proteomics, and other deeply phenotyped datasets. The group’s scientific goals include moving beyond gene discovery to understand disease heterogeneity, subtypes, mechanisms, and comorbidities, with an eye toward precision medicine. Openings are available for Postdoctoral Fellows and Bioinformaticians. The post does not list specific eligibility criteria, funding details, or a deadline, but interested candidates are invited to reach out directly and review the linked application information. Relevant study areas include human genetics, genomics, bioinformatics, genetic epidemiology, computational biology, statistics, and precision medicine.

1 month ago

Articles (18)

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Collaborators (52)

Nancy Cox

Director, Vanderbilt Genetics Institute

Vanderbilt University Medical Center

UNITED STATES

Nathalie Chami

Research Interests

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About

Positions (1)

Postdoctoral Fellow and Bioinformatician Positions in Human Genetics, Genomics, and Precision Medicine

Articles (18)

Meta-analysis of genome-wide associations and polygenic risk prediction for atrial fibrillation in more than 180,000 cases.

Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants

Whole genome sequencing analysis of body mass index identifies novel African ancestry-specific risk allele.

A statistical framework for multi-trait rare variant analysis in large-scale whole-genome sequencing studies.

Genetic subtyping of obesity reveals biological insights into the uncoupling of adiposity from its cardiometabolic comorbidities

Genome-wide association study provides novel insight into the genetic architecture of severe obesity

Genetic determinants and genomic consequences of non-leukemogenic somatic point mutations.

Determinants of mosaic chromosomal alteration fitness

The contribution of functional HNF1A variants and polygenic susceptibility to risk of type 2 diabetes in ancestrally diverse populations

Assessing the contribution of rare variants to complex trait heritability from whole-genome sequence data

Whole genome sequence analysis of platelet traits in the NHLBI Trans-Omics for Precision Medicine (TOPMed) initiative.

Erratum: Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program (The American Journal of Human Genetics (2021) 108(5) (874–893), (S0002929721001348), (10.1016/j.ajhg.2021.04.003))

Genome-wide discovery of genetic loci that uncouple excess adiposity from its comorbidities

Whole-genome sequencing in diverse subjects identifies genetic correlates of leukocyte traits: The NHLBI TOPMed program.

Determinants of penetrance and variable expressivity in monogenic metabolic conditions across 77,184 exomes.

Whole-genome sequencing association analysis of quantitative red blood cell phenotypes: The NHLBI TOPMed program.

The role of polygenic susceptibility to obesity among carriers of pathogenic mutations in MC4R in the UK Biobank population.

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population.

Collaborators (52)

Nancy Cox

Bradley Coe

Eleonora Manitta

Cilius Fonvig

Gregory Kinney

Kerrin S Small

Yuxuan Wang

Cigdem Sevim Bayrak

Elsayed Soliman

Jordi Merino

Zhe Wang

Xueling Sim

Ruth Loos

Heather M Ochs-Balcom

Steven Buyske

Robert Kaplan

Adam Heath

Han Chen

Braxton Mitchell

Mohammad Yaser Anwar

Nicole Soranzo

Daniel Weeks

Ming-Huei Chen

Xihao Li

Nicholas Marston

Jianjun Liu

Shabnam Salimi

Roelof Smit

Joshua Lewis

Karin Hoth

Kazuo Miyazawa

Alexander Rauch

Donald Lloyd-Jones

Jenna Carlson

Morten Salling Olesen

Lise Bjørkhaug Gundersen

Yasminka Jakubek

Merry-Lynn McDonald

Manuel Ferreira

Alexis Battle

Camilla Scheele

Marcel den Hoed

Joanne Curran

Michael Preuss

Nathan Stitziel

Dimitrios Avramopoulos

Anne Justice

Daniel Taliun

Anna Gloyn

Zhonghua Liu

Lam Opal Huang

Martina Müller-Nurasyid

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